Skip to main content
Log in

Effect of fibrin glue on postlaminectomy scar formation

  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Summary

An experimental study in rats has been carried out with the aim of studying the scar formation over the spinal dura in the presence of fibrin glue. Although the main action of fibrin glue is the enhancement of wound healing by increasing the fibrous tissue, our present data suggest that this re-absorbable biomaterial diminishes the epidural scar formation, at least the first two weeks after laminectomy. This finding leads us to consider the use of fibrin glue over spinal duramater when it is likely that reoperation may become necessary in a short period of time after a laminectomy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Barbera J, González J, Esquerdo J, Broseta J, Barcia-Salorio JL (1978) Prophylaxis of the laminectomy membrane. An experimental study in dogs. J Neurosurg 49: 419–424

    PubMed  Google Scholar 

  2. Benoist M, Ficat C, Baraf P, Cauchois J (1980) Postoperative lumbar epiduroarachnoiditis. Diagnostic and therapeutic aspects. Spine 5: 432–436

    PubMed  Google Scholar 

  3. Brodsky AE (1976) Post-laminectomy and post-fusion stenosis of the lumbar spine. Clin Orthop 115: 130–139

    PubMed  Google Scholar 

  4. Bryant MS, Bremer AM, Nguyen TQ (1983) Autogenic fat transplants in the epidural space in routine lumbar spine surgery. Neurosurgery 13: 367–370

    PubMed  Google Scholar 

  5. Cabezudo JM, López A, Bacci F (1985) Symptomatic root compression by a free fat transplant after hemilaminectomy. J Neurosurg 63: 633–635

    PubMed  Google Scholar 

  6. De Villers PD, Booysen EL (1976) Fibrous spinal stenosis: a report on 850 myelograms with a water-soluble contrast medium. Clin Orthop 115: 140–144

    PubMed  Google Scholar 

  7. Gill GG, Sakovich L, Thompson E (1979) Pedicle fat grafts for the prevention of scar formation after laminectomy. An experimental study in dogs. Spine 4: 176–186

    PubMed  Google Scholar 

  8. Jacobs RR, McClain O, Neff J (1980) Control of post laminectomy scar formation. An experimental and clinical study. Spine 5: 223–229

    PubMed  Google Scholar 

  9. Keller JT, Dunsker SB, McWhorter JM, Ongkiko CM, Saunders MC, Mayfield FH (1978) The fate of autologous grafts to the spinal dura. An experimental study. J Neurosurg 49: 412–418

    PubMed  Google Scholar 

  10. Kiviluoto O (1988) Use of free fat transplants to prevent epidural scar formation. An experimental study. Acta Orthop Scand [Suppl] 164: 3–75

    Google Scholar 

  11. Langenskiöld A, Kiviluoto O (1976) Prevention of epidural scar formation after operations on the lumbar spine by means of free fat transplants. Clin Orthop 115: 92–95

    PubMed  Google Scholar 

  12. La Rocca H, McNab I (1974) The laminectomy membrane. Studies in its evolution, characteristics, and prophylaxis in dogs. J Bone Joint Surg [Br] 56 B: 545–550

    Google Scholar 

  13. Lee CK, Alexander H (1984) Prevention of postlaminectomy scar formation. Spine 9: 305–312

    PubMed  Google Scholar 

  14. Martin-Ferrer S (1989) Failure of autologous fat grafts to prevent postoperative epidural fibrosis in surgery of the lumbar spine. Neurosurgery 24: 718–721

    PubMed  Google Scholar 

  15. Nussbaum CE, McDonald JV, Baggs RB (1990) Use of vicryl (polyglactin 910) mesh to limit epidural scar formation after laminectomy. Neurosurgery 26: 649–654

    Article  PubMed  Google Scholar 

  16. Rossitch E Jr, Wilkins RH (1990) The use of fibrin glue in Neurosurgery. In: Wilkins RH, Rengachary SS (eds) Neurosurgery update I. McCraw Hill, New York, pp 195–196

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vaquero, J., Arias, A., Oya, S. et al. Effect of fibrin glue on postlaminectomy scar formation. Acta neurochir 120, 159–163 (1993). https://doi.org/10.1007/BF02112036

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02112036

Keywords

Navigation