Yersinia enterocolitica endocarditis: Case report and literature review

Abstract

Endocarditis is a rare manifestation ofYersinia enterocolitica infection. The case of a 45-year-old man who presented with high fever and in whom prosthetic valveYersinia enterocolitica endocarditis was diagnosed is described. The patient was successfully treated with ceftriaxone plus tobramycin, as proved by negative cultures of the prosthesis removed at the end of therapy. Including the patient reported, only 12 cases ofYersinia enterocolitica endocarditis have been published to date, two of which describe prosthetic cardiac valve endocarditis. The clinical characteristics do not distinguish septicemia from involvement limited to the cardiac valves. Diagnosis, however, has been improved by progress in echocardiography. Prognosis is grave but can be ameliorated if appropriate antimicrobial agents are administered, i.e. the combination of a third-generation cephalosporin plus an aminoglycoside. Fluoroquinolones may also constitute an attractive therapeutic alternative.