Summary
The prebiotic synthesis of His and its dimer has led us to study the possible catalytic properties of His-His. The enhancing effect of His-His has been tested in the dephosphorylation of dAMP, the hydrolysis of oligo(A)12, and the oligomerization of 2′,3′-cAMP.
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Abbreviations
- His-His:
-
histidyl-histidine
- R.t.:
-
retention time
- dAr:
-
deoxyadenosine
- dAMP:
-
2-deoxyadenosine 5′ monosphosphate
- 3′,5′-cAMP:
-
3′,5′-cyclic deoxyadenosine monophosphate
- 2′-AMP:
-
adenosine 2′ monophosphate
- 3′-AMP:
-
adenosine 3′ monophosphate
- 2′,3′-cAMP:
-
2′,3′-cyclic adenosine monophosphate
- RNase A:
-
bovine ribonuclease A
- TEAA:
-
triethylammonium acetate
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Shen, C., Lazcano, A. & Oró, J. The enhancement activites of histidyl-histidine in some prebiotic reactions. J Mol Evol 31, 445–452 (1990). https://doi.org/10.1007/BF02102070
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DOI: https://doi.org/10.1007/BF02102070