Abstract
Respiratory hypersensitivity to ascaris extract aerosol and the potentation of airway resistance increase caused by acetylcholine and histamine challenge produced by this allergen exposition were carried out on four dogs. The effect of disodium cromoglycate on these reactions was also studied.
All animals presented significant respiratory distress with ascaris extract aerosol, which could be avoided by previous exposure to disodium cromoglycate aerosol. The increased response of the bronchial system to acetylcholine and histamine, observed after allergen aerosol, could not be abolished by disodium cromoglycate aerosol.
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Zimmermann, I., Ulmer, W.T. Antigen-induced hypersensitivity of the bronchial system and the influence of disodium cromoglycate. Pneumonologie 153, 95–103 (1976). https://doi.org/10.1007/BF02091430
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DOI: https://doi.org/10.1007/BF02091430