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Die Intersalt Studie: Ergebnisse und Perspektiven

L'étude Intersalt: Résultats et perspectives

The intersalt study: Results and perspectives

  • Published:
Sozial- und Präventivmedizin

Zusammenfassung

Die bei 10079 Teilnehmern der an 52 Zentren in 32 Ländern durchgeführten Intersalt Studie erhobenen Daten zeigen, dass die bisher postulierten linearen Beziehungen zwischen Elektrolytausscheidung und Hypertonie der Vergangenheit angehören. Darüber hinaus leisten Übergewicht und Alkoholkonsum einen unabhängigen Beitrag zur Höhe des individuellen Blutdruckes. Die Studienergebnisse müssen im Rahmen einer differenzierten epidemiologischen Bewertungsweise interpretiert werden.

Résumé

Cet article a porté sur 10079 participants provenant de 52 centres répartis dans 32 pays. Ces résultats, récemment publiés, montrent qu'une association linéaire simple entre sel alimentaire et tension artérielle n'est plus un modèle pertinent. De plus, la surcharge pondérale et la consommation d'alcool agissent indépendamment sur la pression artérielle. Les résultats de l'étude doivent être interprétés prudemment dans le cadre d'une analyse épidémiologique soigneuse.

Summary

The recently published Intersalt Study comprising 10079 participants from 52 study centers in 32 countries demonstrated that the simple linear relationship so far postulated for the association between electrolytes and hypertension is history. In addition overweight and alcohol consumption make an independent contribution to the level of individual blood pressures. The study results have to be interpreted carefully in the framework of a differentiated epidemiologic analysis.

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Literaturverzeichnis

  1. Dahl LK. Possible role of salt intake in the development of essential hypertension. In: Bach, Kottier (eds.) Essential Hypertension. Berlin: Springer-Verlag, 1960.

    Google Scholar 

  2. Prineas RJ, Blackburn H. Clinical and epidemiologic relationships between electrolytes and hypertension. NIH Workshop on Nutrition and Hypertension. Horan MJ, Blaustein M. Dunbar JB et al. (eds.) New York: Biomed Information Corp., 1985.

    Google Scholar 

  3. Kochmachi Y, Iida M, Shimamoto T. Geographic and occupational comparisons of risk factors in cardiovascular diseases in Japan. Jpn Circ J 1971; 35: 189–207.

    PubMed  Google Scholar 

  4. Saski N. High blood pressure and the salt intake of the Japanese. Jpn Heart J 1982; 3: 313–324.

    Google Scholar 

  5. Gleiberman L. Blood pressure and dietary salt in human populations. Ecol Food Nutr 1973; 2: 143–156.

    Google Scholar 

  6. Harlan WR, Hull Al, Schmouder RL, Landis JR, Thompson FR, Larkin FA. Blood pressure and nutrition in adults. Am J Epidemiol 1984; 120: 17–28.

    PubMed  Google Scholar 

  7. Harlan WR, Landis JR, Schmouder RL, Goldstein NG, Harlan LC. Blood lead and blood pressure: relationship in adolescent and adult U.S. populations. JAMA 1985; 253: 530–534.

    PubMed  Google Scholar 

  8. McCarron D, Morris CD, Henry HJ, Stanton JL. Blood pressure and nutrient intake in the United States. Science 1984; 224: 1392–1398.

    PubMed  Google Scholar 

  9. Schlierf et al. Salt and hypertension. Data from the Heidelberg Study. Am J Nutr 1980; 33: 872–875.

    Google Scholar 

  10. Heine H, Heinemann L, Barth Wm, Faulhaber HD. Salt consumption and salt intervention studies in the GDR. In: Electrolyte Intake and Hypertension, Ganten D, Rettig R, Luft F. C. (eds.) Berlin: Springer-Verlag. 1988.

    Google Scholar 

  11. The Intersalt Cooperative Research Group. An International Cooperative Study on the Relation of Blood Pressure to Electrolyte Excretion in Populations. I. Design and Methods. Journal of Hypertension 1986; 4: 781–787.

    Google Scholar 

  12. Elliott P, Stamler R. Manual of Operations for «INTERSALT», an International Cooperative Study on the Relation of Sodium and Potassium to Blood Pressure. In: Controlled Clinical Trials 9, 1988: 1–118.

    PubMed  Google Scholar 

  13. The Intersalt Cooperative Research Group. INTERSALT. An International Study of Electrolyte Excretion and Blood Pressure; Results for 24 Hour Urinary Sodium and Potassium. Brit Med Journal 1988; 297: 319–328.

    Google Scholar 

  14. Laaser U, Wenzel H, Allhoff P. Kardiovaskuläre Interventionsstudien: Probleme und Perspektiven. In: Präventive Medizin, Symposium der Stiftung Hufeland-Preis, Köln und der Akademie der Wissenschaften und der Literatur. Mainz, Schölmerich P, Theile U, v. Troschke J (Hrsg.) Stuttgart: Gustav Fischer Verlag 1988: 117–129.

    Google Scholar 

  15. Rothman KJ. Modern Epidemiology, Boston: Little, Brown and Company, 1986: 20.

    Google Scholar 

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Laaser, U., Luft, F.C., Siegel, M. et al. Die Intersalt Studie: Ergebnisse und Perspektiven. Soz Präventivmed 34, 1–3 (1989). https://doi.org/10.1007/BF02084743

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  • DOI: https://doi.org/10.1007/BF02084743

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