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The use of pediatric cadaver kidneys in renal transplantation (Experience with 97 cases and comparison with adult kidneys)

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Abstract

Pediatric cadaver donors are an important pool of kidneys for human allotransplantation. Experiences with 97 transplantations of pediatric cadaveric kidneys (age: 4 months to 15 years) and comparison with 230 transplantations of adult kidneys (age: 16–25 and 40–68 years) are presented. The cumulative patient survival was similar in both groups, however, the graft survival was significantly lower in the pediatric donor group (p<0.05). This difference was established almost exclusively within the first 3 months after transplantation. In this group the percentage of technical complications in the first month was higher (13.4%) than in the adult kidney group (6.5%). The analysis of the whole pool of harvested kidneys shows a significantly higher rate of transplanted kidneys in the pediatric group (61%) as compared with the adult group (44.7%). In both groups the mode of arterial vascular anastomosis (end-to-end or end-to-side) does not influence the graft survival.

Further investigations on pediatric donor kidneys are necessary. The utilization of pediatric cadaveric kidneys for transplantation should be increased because 20–25% of all potential kidney donors are younger than 15 years.

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Authors and Affiliations

  1. Kidney Transplantation Center, Berlin-Friedrichshain, Department of Urology, Division of Experimental Organ Transplantation, Humboldt-University (Charité), Berlin, GDR

    L. G. Managadze, H. Oesterwitz, D. Scholz, G. May & M. Mebel

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  1. L. G. Managadze
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  2. H. Oesterwitz
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  3. D. Scholz
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  4. G. May
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  5. M. Mebel
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Managadze, L.G., Oesterwitz, H., Scholz, D. et al. The use of pediatric cadaver kidneys in renal transplantation (Experience with 97 cases and comparison with adult kidneys). International Urology and Nephrology 13, 95–104 (1981). https://doi.org/10.1007/BF02082078

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  • DOI: https://doi.org/10.1007/BF02082078

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