Abstract
The author carried out histological and immunofluorescence studies on 15 autopsied cases of diabetic glomerulosclerosis. In the nodular lesion of glomerulosclerosis IgG, C', IgM and fibrin were found in the glomeruli and at some sites also in the wall of the arterioles. In diffuse lesion of glomerulosclerosis IgG, C] and IgM were demonstrated on the glomerular basement membrane when the mesangium increased only slightly and thickening of the basement membrane of the glomeruli predominated. On the basis of her studies the author raises the possible immunological origin of diabetic glomerulosclerosis.
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Beregi, E. Immunomorphological study of renal changes of diabetic individuals. International Urology and Nephrology 5, 179–186 (1973). https://doi.org/10.1007/BF02081922
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DOI: https://doi.org/10.1007/BF02081922