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Co-existence of abdominal aortic aneurysms and intracranial aneurysms

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Summary

The occurrence of abdominal aortic aneurysms (AAAs) and intracranial aneurysms (IAs) in the same patient and in the same family was studied among 89 patients with AAAs and 485 patients with IAs. Among the AAA-patients two had IAs themselves and five had IAs in the family, whereas three IA-patients had AAAs themselves and eight had AAAs in the family. Moreover, one of the patients with both AAA and IA had a blood relative with AAA, and in six of the families with both types of aneurysms there were more than two subjects with aneurysms. The results indicate, that AAAs and IAs may have a common aetiologic factor.

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References

  1. Auerbach O, Garfunkel L (1980) Atherosclerosis and aneurysm of aorta in relation to smoking habits and age. Chest 78: 805–809

    PubMed  Google Scholar 

  2. Bannerman RM, Ingall GB, Graf CJ (1970) The familial occurrence of intracranial aneurysm. Neurology 20: 283–292

    PubMed  Google Scholar 

  3. Bolander H, Hassler O, Liliequist B, West K (1978) Cerebral aneurysm in an infant with fibromuscular hyperplasia of the renal arteries. J Neurosurg 49: 756–759

    PubMed  Google Scholar 

  4. Burnett HF, Bledsoe JH, Char F, Williams GD (1973) Abdominal aortic aneurysmectomy in a 17-year-old patient with Ehlers-Danlos syndrome: Case report and review of the literature. Surgery 74: 617–620

    PubMed  Google Scholar 

  5. Busuttil RW, Cardenas A (1982) Collagenase and elastase activity in the pathogenesis of abdominal aortic aneurysms. In: Bergan JJ, Yao JST (eds) Aneurysms, diagnosis and treatment. Grune and Stratton, New York, pp 83–94

    Google Scholar 

  6. Carlsson T, Sternby NH (1964) Aortic aneurysms. Acta Chir Scand 127: 466–473

    PubMed  Google Scholar 

  7. Chester AC, Harris TP, Schreiner GE (1977) Poycystic kidney, disease. Am Fam Physician 16: 94–101

    PubMed  Google Scholar 

  8. Crawford T (1959) Some observations on the pathogenesis and natural history of intracranial aneurysms. J Neurol Neurosurg Psychiat 22: 259–266

    PubMed  Google Scholar 

  9. Curtis T, Jimeney TA (1968) Intracranial aneurysm with panhypopituitarism with associated aneurysms of thoracic and abdominal aortas. JAMA 203: 982–984

    PubMed  Google Scholar 

  10. Darling RC, Messina CR, Brewster DC, Ottinger IW (1977) Autopsy study of unoperated abdominal aortic aneurysms. The case for early resection. Circulation 56: 161–163

    Google Scholar 

  11. Estes IE Jr (1950) Abdominal aortic aneurysms: a study of one hundred and two cases. Circulation 2: 258–264

    PubMed  Google Scholar 

  12. Fields WS, Gonzalez-Angulo A (1965) Multiple cerebral dilatations of cerebral and peripheral arteries. Texas Med 61: 899–905

    Google Scholar 

  13. Finney HL, Roberts TS, Anderson RE (1976) Giant intracranial aneurysm associated with Marfan's syndrome. Case report. J Neurosurg 45: 342–347

    PubMed  Google Scholar 

  14. Hashimoto I (1977) Familial intracranial aneurysms and cerebral vascular anomalies. J Neurosurg 46: 419–427

    PubMed  Google Scholar 

  15. Hepp W, Bercher M (1982) Marfan-Syndrome and Aneurysmen der Aorta abdominalis. Vasa 10: 53–57

    Google Scholar 

  16. Jain KK (1974) Familial intracranial aneurysms. Review of literature and presentation of six new cases. Acta Neurochir (Wien) 30: 129–137

    Google Scholar 

  17. Jaksche H (1986) Familiar intracranial aneurysms. Four carotid aneurysms among a family with ten members. Zbl Neurochir 47: 351–353

    Google Scholar 

  18. Kagan AR, Sternby NH, Hemur K, Vanecek R, Vihert AN (1976) Atherosclerosis of the aorta and coronary arteries in five towns. Bull WHO 53

  19. Massumi RA, Lowe EW, Misonik LF, Just H, Tawakkol A (1967) Multiple aortic aneurysms (thoracic and abdominal) in twins with Marfan's syndrome. Fatal rupture during pregnancy. J Thorac Cariovas Surg 53: 223–230

    Google Scholar 

  20. Moore MT (1965) Multiple cerebral aneurysms in a patient with an abdominal aortic aneurysms. Report of a case. J Neurosurg 23: 626–629

    PubMed  Google Scholar 

  21. Moore WS, Malone JM (1982) Mycotic aneuysms. In: Bergan JJ, Jao JST (eds) Aneurysms, diagnosis and treatment. Grune and Stratton, New York, pp 581–595

    Google Scholar 

  22. Morooka Y, Waga S (1983) Familial intracranial aneurysms: Report of four families. Surg Neurol 19: 260–262

    PubMed  Google Scholar 

  23. Neil-Dwyer G, Bartlett JR, Nicholls AC, Narcisi P, Pope FM (1983) Collagen deficiency and ruptured cerebral aneurysms. J Neurosurg 59: 16–30

    PubMed  Google Scholar 

  24. Nevins MA, Lyon LJ, Kim JM (1978) Multiple arterial abnormalities presenting as pulsatile tinnitus. J Med Soc, New Jersey 75: 467–470

    Google Scholar 

  25. Norrgård Ö, Cedergren B, Ängquist K-A, Beckman L (1984) Blood groups and HLA antigens in patients with abdominal aortic aneurysms. Human Heredity 34: 9–13

    PubMed  Google Scholar 

  26. Norrgård Ö, Fröhlander N, Beckman G, Ängquist K-A (1984) Association between haptoglobin groups and aortic abdominal aneurysms. Human Heredity 34: 166–169

    PubMed  Google Scholar 

  27. Norrgård Ö, Rais O, Ängquist K-A (1984) Familial occurrence of abdominal aortic aneurysms. Surgery 95: 650–656

    PubMed  Google Scholar 

  28. Norrgård Ö, Ängquist K-A, Johnson O (1985) Familial aortic aneurysms: serum concentration of triglyceride, cholesterol, HDL-cholesterol and (VLDL + LDL)-cholesterol. Br J Surg 72: 113–116

    PubMed  Google Scholar 

  29. Prockop DJ, Kivirikko KI (1984) Hereditable diseases of collagen. New Eng J Med 311: 376–386

    PubMed  Google Scholar 

  30. Roberts WC (1982) Pathology of arterial aneurysms. In: Bergan JJ, Yao JST (eds) Aneurysms, diagnosis and treatment. Grune and Stratton, New York, pp 17–43

    Google Scholar 

  31. Rubinstein MK, Cohen NH (1964) Ehlers-Danlos syndrome associated with multiple intracranial aneurysms. Neurology 14: 125–132

    PubMed  Google Scholar 

  32. Sahs AL (1966) Observations on the pathology of saccular aneurysms. J Neurosurg 24: 792–806

    PubMed  Google Scholar 

  33. Sahs AL, Perret G, Locksley HB, Nishioka H, Shultety FM (1966) Premliminary remarks on subarachnoidal hemorrhage. J Neurosurg 24: 782–788

    PubMed  Google Scholar 

  34. Sekhar LN, Heros RC (1982) Origin, growth and rupture of saccular aneurysms: a review. Neurosurg 8: 248–260

    Google Scholar 

  35. Stavenow L (1979) Familial occurence of intracranial aneurysms. Acta Med Scand 206: 197–200

    PubMed  Google Scholar 

  36. Stehbens WE (1962) Cerebral aneurysms and congential abnormalities. Australas Ann Med 11: 102–112

    PubMed  Google Scholar 

  37. Tilson MD, Seashore MR (1984) Fifty families with abdominal aortic aneurysms in two or more firstorder relatives. Am J Surg 147: 551–553

    PubMed  Google Scholar 

  38. Tilson MD, Stansel HC (1980) Differences in results for aneurysms vs occlusive disease after bifurcation grafts: Results of 100 elective grafts. Arch Surg 115: 1173–1175

    PubMed  Google Scholar 

  39. Wakabayashi T, Fujita S, Ohbora Y, Suyama T, Tamaki N, Matsumoto S (1983) Polycystic kidney disease and intracranial aneurysms. Early angiographic diagnosis and early operation for the unruptured aneurysm. J Neurosurg 58: 488–491

    PubMed  Google Scholar 

  40. Zarins CK, Glagov S (1982) Aneurysms and obstructive plaques: differing local responses to atherosclerosis. In: Bergan JJ, Yao JST (eds) Aneurysms, diagnosis and treatment. Grune and Stratton, New York, pp 45–60

    Google Scholar 

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Norrgård, Ö., Ängqvist, K.A., Fodstad, H. et al. Co-existence of abdominal aortic aneurysms and intracranial aneurysms. Acta neurochir 87, 34–39 (1987). https://doi.org/10.1007/BF02076012

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