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Eosinophilic gastroenteritis presenting with colitis and cholangitis

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Summary

Eosinophilic gastroenteritis (EG) is a rare condition that most commonly affects the stomach and intestine. Large bowel involvement has also been described. We report a case of EG presenting with colitis and cholangitis. This is the first case of associated cholangitis demonstrated radiologically and histologically. Simultaneous biliary and gastrointestinal tract involvement suggest a common link between EG and hypereosinophilic syndrome (HES). However, HES requires high peripheral hypereosinophilia and several organs including gastrointestinal tract, lung, heart, infiltrated with eosinophils. The patient's condition improved with corticosteroids.

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References

  1. Madjlessi SHM, Sivak MV, Farmer RG: Hypereosinophilia, ulcerative colitis, sclerosing cholangitis, and bile duct carcinoma. Am J Gastroenterol 81:483–485, 1986

    PubMed  Google Scholar 

  2. Anthonisen P, Riis P: Eosinophilic granulocytes in the rectal mucus of patients with ulcerative colitis and Crohn's disease of the ileum and colon. Scand J Gastroenterol 6:731–734, 1971

    PubMed  Google Scholar 

  3. Wiesner RH, La Russo NF: Clinicopathologic features of syndrome of primary sclerosing cholangitis. Gastroenterology 79:200–206, 1980

    PubMed  Google Scholar 

  4. Klein NC, Hargrove RL, Sleisenger MH, Jeffries GH: Eosinophilic gastroenteritis. Medicine 49:299–318, 1970

    PubMed  Google Scholar 

  5. Fauci AS, Harley JB, Roberts WC, Ferrans VJ, Gralnick HR, Bjornson BH: The idiopathic hypereosinophilic syndrome. Clinical, pathophysiologic, and therapeutic considerations. Ann Intern Med 97:78–92, 1982

    PubMed  Google Scholar 

  6. Riisager PM: Eosinophil leucocytes in ulcerative colitis. Lancet 2:1008–1009, 1959

    Google Scholar 

  7. Juhlin L: Basophil and eosinophil leukocytes in various internal disorders. Acta Med Scand 174:249–255, 1963

    PubMed  Google Scholar 

  8. Balzer K, Hotz J, Goebell H: Eosinophilie als Leitsymptom der primar sklerosierenden cholangitis Z Gastrenterol 18:89–93, 1980

    Google Scholar 

  9. Hardy WR, Anderson RE: The hypereosinophilic syndrome. Ann Intern Med; 68:1220–1228, 1968

    PubMed  Google Scholar 

  10. Chusid MJ, Dale DC, Burton CW, West BC, Wolf SM: The hypereosinophilic syndrome. Analysis of fourteen cases with review of the literature. Medicine 54:1–27, 1975

    PubMed  Google Scholar 

  11. Scheurlen M, Mork H, Weber P: Hypereosinophilic syndrome resembling chronic inflammatory bowel disease with primary sclerosing cholangitis. J Clin Gastroenterol 14:59–63, 1992

    PubMed  Google Scholar 

  12. Talley NT, Shorter RG, Phillips SF, Zinmeister AR: Eosinophilic gastroenteritis: A clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues. Gut 31:54–58, 1990

    PubMed  Google Scholar 

  13. Kayser R: Zur Kenntnis der allergischen Affektionen des Verdauungskanal vom Standpunkt des Chirurgen aus. Arch Klin Chir 188:36–74, 1937

    Google Scholar 

  14. Robert F, Omura E, Durant JR: Mucosal eosinophilic gastroenteritis with systemic involvement. Am J Med 62:139–143, 1977

    PubMed  Google Scholar 

  15. Rumans MC, Lieberman DA: Eosinophilic gastroenteritis presenting with biliary and duodenal obstruction. Am Coll Gastroenterol 82:775–778, 1987

    Google Scholar 

  16. Splechler SJ, Graeme-Cook FM: A 24-year-old man with asthma and bouts of epigastric pain, nausea, and vomiting. N Engl J Med 326:1342–1349, 1992

    PubMed  Google Scholar 

  17. Naylor AR, Pollet JE: Eosinophilic colitis. Dis Colon Rectum 28:615–618, 1985

    PubMed  Google Scholar 

  18. Farahvash MJ, Bastani B, Farahvash MR, Irvanlou G: Eosinophilic gastroenteritis presenting with biliary and partial duodenal obstruction. Am J Gastroenterol 85:1022–1024, 1990

    PubMed  Google Scholar 

  19. Levesque H, Elie-Legrand MC, Thorel JM, Touchais O, Gancela, Hecketsweiller P, Courtois H: Syndrome hyperéosinophilique idiopathique à manifestations digestives prédominantes ou gastroentérite à éosinophiles? Gastroenterol Clin Biol 14:586–588, 1990

    PubMed  Google Scholar 

  20. Weisberg SC, Crosson JT: Eosinophilic gastroenteritis: Report of a case of thirty-two years' duration. Am J Dig Dis 18:1005–1014, 1973

    PubMed  Google Scholar 

  21. Lee CM, Changchien CS, Chen PC, Lin DY, Sheen IS, Wang CS, Tai DI, Sheen-Chen JM, Chen WJ, Wu CS: Eosinophilic gastroenteritis: 10 years' experience. Am J Gastroenterol 88:70–74, 1993

    PubMed  Google Scholar 

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Schoonbroodt, D., Horsmans, Y., Laka, A. et al. Eosinophilic gastroenteritis presenting with colitis and cholangitis. Digest Dis Sci 40, 308–314 (1995). https://doi.org/10.1007/BF02065415

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  • DOI: https://doi.org/10.1007/BF02065415

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