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Ogilvie's syndrome: A new approach to an old problem

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Diseases of the Colon & Rectum

Abstract

PURPOSE: This study was designed to determine the value of intravenous neostigmine in achieving adequate colonic decompression in patients with Ogilvie's syndrome. METHODS: A prospective study was undertaken in 12 consecutive patients (median age, 60 (range, 38–98) years) with contrast enema-proven Ogilvie's syndrome (median duration, four (range, two–nine) days) RESULTS: Satisfactory clinical decompression of large bowel distention was attained in 11 patients, although one required colectomy for subsequent recurrence and ischemia. CONCLUSION: These results support the theory that many cases of Ogilvie's syndrome are the result of excessive large bowel parasympathetic suppression rather than sympathetic overactivity.

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References

  1. Ogilvie H. Large-intestine colic due to sympathetic deprivation: a new clinical syndrome. BMJ 1948;2:671–3.

    Article  PubMed  CAS  Google Scholar 

  2. Dorudi S, Berry AR, Kettlewell MG. Acute colonic pseudo-obstruction. Br J Surg 1992;79:99–103.

    PubMed  CAS  Google Scholar 

  3. Vanek VW, Al-Salti M. Acute pseudo-obstruction of the colon (Ogilvie's syndrome): an analysis of 400 cases. Dis Colon Rectum 1986;29:203–10.

    PubMed  CAS  Google Scholar 

  4. Datta SN, Havard TJ, Stephenson BM, Salaman JR. Acute colonic pseudo-obstruction. Lancet 1993;341:690.

    PubMed  CAS  Google Scholar 

  5. Hutchinson R, Griffiths C. Acute colonic pseudoobstruction: a pharmacological approach. Ann R Coll Surg Engl 1992;74:364–7.

    PubMed  CAS  Google Scholar 

  6. Longo WE, Vernava AM III. Prokinetic agents for lower gastrointestinal motility disorders. Dis Colon Rectum 1993;36:696–708.

    PubMed  CAS  Google Scholar 

  7. Stephenson BM, Morgan AR, Drake N, Salaman JR, Wheeler MH. Parasympathomimetic decompression of acute colonic pseudo-obstruction. Lancet 1993;342:1181–2.

    PubMed  CAS  Google Scholar 

  8. Child CS. Glycopyrrolate and the bowel. Anaesthesia 1984;39:495–6.

    PubMed  CAS  Google Scholar 

  9. Child CS. Prevention of neostigmine-induced colonic activity: a comparison of atropine and glycopyrronium. Anaesthesia 1984;39:1083–5.

    PubMed  CAS  Google Scholar 

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Read at the meeting of The American Society of Colon and Rectal Surgeons, Orlando, Florida, May 8 to 13, 1994.

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Stephenson, B.M., Morgan, A.R., Salaman, J.R. et al. Ogilvie's syndrome: A new approach to an old problem. Dis Colon Rectum 38, 424–427 (1995). https://doi.org/10.1007/BF02054234

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  • DOI: https://doi.org/10.1007/BF02054234

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