Abstract
A preliminary survey of the genusPenicillium reveals that production of a trem-orgenic toxin is confined to certain species of the Subsection Fasciculata, Section Asymmetrica. The most intense toxin synthesis was noted in strains ofP. crustosum, P. cyclopium, P. grannulatum, andP. palitans.
Zusammenfassung
Eine vorläufige Übersicht der GattungPenicillium zeigt, daß die Erzeugung eines tremorgenischen Toxins an gewisse Arten der Subsektion Fasciculata, Section Asymmetrica beschränkt ist. Die kräftigste Toxinsynthesis war inP. crustosum, P. cyclopium P. granulatum, undP. palitans beobachtet.
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References
Bonner, W. A., Burke, N. I., Fleck, W. E., Hill, R. K., Joule, J. A., Sjöberg. B. &Zalkow, J. H. (1964) The absolute configurations of tremetone and toxol,Tetrahedron 20:1419–1425.
Ciegler, A. (1969) A tremorgenic toxin fromPenicillium palitans. Appl. Microbiol. (In press).
Cunningham, K. G. &Freeman, G. G. (1953) The isolation and some chemical properties of viridicatin, a metabolic product ofPenicillium viridicatum Westling.Biochem. J. 53:328–332.
Everett, G. M., Blockus, L. E. &Shepperd, I. M. (1956) Tremor induced by tremorine and its antagonism by anti-Parkinson drugs.Science 124:79.
Raper, K. B. &Thom, C. (1949) A manual of the Penicillia, p. 540. The Williams & Wilkins Co., Baltimore, Md.
Wilson, B. J. &Wilson, C. H. (1964) Toxin fromAspergillus flavus: Production on food materials of a substance causing tremors in mice.Science 144:177–178.
Wilson, B. J., Wilson, C. H. &Hayes, A. W. (1968) Tremorgenic toxin fromPenicillium cyclopium grown on food materials.Nature 220:77–78.
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This is a laboratory of the Northern Utilization Research and Development Division, Agricultural Research Service, U.S. Department of Agriculture.
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Ciegler, A., Pitt, J.I. Survey of the genus penicillium for tremorgenic toxin production. Mycopathologia et Mycologia Applicata 42, 119–124 (1970). https://doi.org/10.1007/BF02051832
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DOI: https://doi.org/10.1007/BF02051832