Abstract
We identified 47 patients with nonocclusive ischemia of the large intestine over a seven-year period. The mean age at presentation was 56.2 years, with a 2∶2∶1 male predominance. Associated medical illnesses were diabetes (17 percent), renal failure (5 percent), and hematologie disorders (5 percent). Six patients developed ischemic colitis after aortic surgery. The mean delay in diagnosis was 1.8 days (range, three hours to 23 days). The right colon was involved in 21 patients (46 percent). Overall, 15 of 16 patients were successfully treated non-operatively with bowel rest and antibiotics; one patient who was managed nonoperatively died. Among the 31 requiring intestinal resection, enteric continuity was reestablished in 14. Second-look laparotomy in eight patients revealed further ischemia in two (20 percent). Mortality in the operative group was 29 percent (9 of 31). No patient has developed recurrent ischemia (mean follow-up, 5.3 years). Ischemic colitis often occurs without an obvious predisposing event, may involve all segments of the large intestine, and frequently requires surgery. While its course may be self-limited, elderly and diabetic patients, as well as those developing ischemia following aortic surgery or hypotension, continue to have a poor prognosis.
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Guttmorson NL, Bubrick MP. Mortality from ischemic colitis. Dis Colon Rectum 1989;32:469–72.
Abel ME, Russell TR. Ischemic colitis: comparison of surgical and nonoperative management. Dis Colon Rectum 1983;26:113–5.
Welch GH, Shearer MG, Imrie CW, Anderson JR, Gilmour DG. Total colonic ischemia. Dis Colon Rectum 1986;29:410–2.
West BR, Ray JE, Gathright JB. Comparison of transient ischemic colitis with that requiring surgical treatment. Surg Gynecol Obstet 1980;151:366–8.
Boley SJ. Colonic ischemia—25 years later. Am J Gastroenterol 1990;85:931–4.
Magnusson I, Rieger A, Nilsson R. Clinical appearance in severe ischemic colitis. Acta Chir Scand 1990;156:241–5.
Kaminski DL, Keltner RM. Ischemic colitis. Arch Surg 1973;106:558–63.
Reeders JW, Tytgat GN, Rosenbusch G, Gramata S. Ischemic colitis. The Hague: Martinus Hijhoff, 1984: 17–28, 145–51.
Tada J, Misaki F, Kawai K. Analysis of the clinical features of ischemic colitis. Gastroenterol Jpn 1983;18:204–9.
Mentha G, Robert J, Rohner A, Rohner A. Results of surgical treatment of ischemic colitis. Helv Chir Acta 1991;57:777–82.
Bynum TE, Jacobson ED. Vascular disorders of the large bowel. In: Kirschner JB, Shorter RG, eds. Diseases of the colon, rectum and anus. Baltimore: Williams and Wilkins, 1988:537–49.
Barcewicz PA, Welch JP. Ischemic colitis: current trends. Conn Med 1979;43:695–8.
Sakai L, Keltner R, Kaminski D. Spontaneous and shock associated ischemic colitis. Am J Surg 1980;140:755–60.
Landreneau RJ, Fry WJ. The right colon as a target organ of non-occlusive mesenteric ischemia. Arch Surg 1990;125:591–4.
Welling RE, Roedersheimer LR, Arbaugh JJ, Cranley JJ. Ischemic colitis following repair of ruptured abdominal aortic aneurysm. Arch Surg 1985;120:1368–70.
Hagihara PF, Ernst CB, Griggen WO. Incidence of ischemic colitis following abdominal aortic reconstruction. Surg Gynecol Obstet 1979;149:571–3.
Kim MW, Hundahl SA, Dang CR, McNamara JJ, Straehley CJ, Whelan TJ Jr. Ischemic colitis after aortic aneurysmectomy. Am J Surg 1983;145:392–5.
Schroder T, Christofferson JK, Andersen J,et al. Ischemic colitis complicating reconstruction of the abdominal aorta. Surg Gynecol Obstet 1985;160:299–303.
Kozarek RA, Ernest DL, Silverman ME. Air pressure induced colon injury during diagnostic colonoscopy. Gastroenterology 1980;78:7–14.
Kaleya RN, Boley SJ. Colonic ischemia. Perspect Colon Rectal Surg 1990;3:62–7.
Rosen IB, Cooter MD, Ruderman RL. Necrotizing colitis. Surg Gynecol Obstet 1973;137:645–9.
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Read at the meeting of The American Society of Colon and Rectal Surgeons, Boston, Massachusetts, May 12 to 17, 1991.
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Longo, W.E., Ballantyne, G.H. & Gusberg, R.J. Ischemic colitis: Patterns and prognosis. Dis Colon Rectum 35, 726–730 (1992). https://doi.org/10.1007/BF02050319
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DOI: https://doi.org/10.1007/BF02050319