Summary
The data presented in the present study suggest that neither the ascending noradrenergic fibres confined to the MFB nor the serotonergic fibres originating in or passing through the mesencephalic raphe are essential for periodicity in body temperature. Both control and experimental groups, i.e., rats subjected to medial forebrain bundle or raphe ablation presented circadian periodicity in body temperature and neither the phase, amplitude or overall mean of experimentals differed significantly from controls.
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References
F.K. Stephan and I. Zucker. Proc. natl Acad. Sci. (Wash.)69, 1583 (1972).
R.Y. Moore and V.B. Eichler, Psychoneuroendocrinology1, 265 (1976).
M. Jouvet, Science163, 32 (1969).
F. Héry, J.F. Pujol, M. Lopez, J. Macon and J. Glowinski, Brain Res.21, 319 (1970).
B. Srebro and S.A. Lorens, Brain Res.89, 303 (1975).
S.T. Breisch, F.P. Zemlan and B.G. Hoebe, Science192, 382 (1976).
N.K. Popova and L.N. Maslova and E.V. Naumenko, Brain Res.47, 61 (1972).
I. Vermes, D. Molonar and G. Telegdy, Acta physiol. hung.43, 27 (1973).
M. Héry, E. Laplante and C. Kardon, Endocrinology102, 1019 (1978).
M.A. Salch, P.J. Haro and C.M. Winget, J. interdiscipl. Cycle Res.8, 341 (1977).
J.D. Dunn, A.J. Castro and J.A. McNulty, Neurosci. Lett.6, 345 (1977).
J. de Groot, in: The Rat Forebrain in Stereotoxic Coordinates, p. 40. North-Holland Publ., Amsterdam 1959.
M.C. Fioretti, C. Reccardi, E. Menconi and L. Martin, Life Sci.14, 2111 (1974).
G.H. Miles, Ann. N.Y. Acad. Sci.98, 858 (1962).
J.D. Dunn, A.J. Castro and J.A. McNulty, Soc. Neurosci.3 343, 1977.
M. Jouvet, Adv. Pharm.6B, 265 (1968).
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Dunn, J.D., Castro, A.J. & McNulty, J.A. Failure of medial forebrain bundle or raphe ablation to alter the daily temperature rhythm of the rat. Experientia 34, 1588–1589 (1978). https://doi.org/10.1007/BF02034691
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DOI: https://doi.org/10.1007/BF02034691