Cerebral infarctions due to CNS infection withEnterobacter sakazakii

Abstract

Recent reports have implicatedEnterobacter sakazakii, a gramnegative enteric bacillus, in neonatal sepsis and meningitis [1–4]. Cases of severe central nervous system involvement, including ventriculitis, brain abscess, infarction, and cyst formation, have been described [1]. We present serial head CT findings in a case of neonatalE. sakazakii meningitis complicated by a ring enhancing cerebral infarction which mimicked abscess formation. In meningitis secondary to this agent, a recognized pattern of cerebral hypodensity with or without cystic degeneration late in the course of the infection is likely to represent cerebral infarction rather than an abscess especially if there is a lack of culture evidence of a bacterial infection.