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In vitro activity of ticarcillin plus clavulanic acid against bacteria isolated in three centers

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Abstract

Over 10,000 bacterial isolates were tested against ticarcillin alone or combined with clavulanic acid (2.0μg/ml). Of 5,295Enterobacteraceae, 72% were susceptible to ticarcillin alone, whereas 91% were susceptible to the combination.Bacteroides fragilis andBacteroides melaninogenicus isolates were more susceptible to the combination. The activity of ticarcillin against other microorganisms was not profoundly influenced.

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Authors and Affiliations

  1. The Clinical Microbiology Institute, P.O. Box 947, 97062, Tualatin, Oregon, USA

    A. L. Barry

  2. The Ohio State University Medical Center, 43210, Columbus, Ohio, USA

    L. W. Ayers

  3. The Cleveland Clinic Foundation, 44106, Cleveland, Ohio, USA

    T. L. Gavan

  4. St. Francis Hospital, 67214, Wichita, Kansas, USA

    E. H. Gerlach

  5. Kaiser-Permanente Regional Laboratory, 97015, Clackamas, Oregon, USA

    R. N. Jones

Authors
  1. A. L. Barry
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  2. L. W. Ayers
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  3. T. L. Gavan
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  4. E. H. Gerlach
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  5. R. N. Jones
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Barry, A.L., Ayers, L.W., Gavan, T.L. et al. In vitro activity of ticarcillin plus clavulanic acid against bacteria isolated in three centers. Eur. J, Clin. Microbiol. 3, 203–206 (1984). https://doi.org/10.1007/BF02014879

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  • DOI: https://doi.org/10.1007/BF02014879

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