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Antihepatoxic constituents ofGarcinia kola seeds

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Summary

Kolaviron, a fraction of defatted methanolic extract and biflavanones ofGarcinia kola seeds significantly antagonized the lethal poisoning of mice with phalloidin. Garcinia biflavanones GB1, GB2 and kolaflavanone were isolated as the active constituents.

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Literatur

  1. Iwu, M.M., unpublished evaluation; Patent Application 426/82, Federal Republic of Nigeria (1982).

  2. Aplin, R.T., Blasdale, J.K.C., Halsall, T.G., and Hornby, G.M., J. chem. Soc.C (1967) 246.

  3. Cotterhill, P.J., Scheinmann, F., and Stenhouse, I.A., J. chem. Soc. Perkin Trans.I (1978) 532.

    Article  Google Scholar 

  4. Iwu, M.M., Planta Medica45 (1982) 147.

    Article  Google Scholar 

  5. Iwu, M.M., and Igboko, O.A., J. natn. Prod. (Lloydia)45 (1982) 650.

    Article  CAS  Google Scholar 

  6. Hussain, R.A., Parimoo, A.G., and Waterman, P.G., Planta Medica44 (1982) 78.

    Article  CAS  PubMed  Google Scholar 

  7. Tuchweber, B., Sieck, R., and Trost, W., Tox. appl. Pharmac.51 (1979) 265.

    Article  CAS  Google Scholar 

  8. Frimmer, M. Phalloidin, a membrane specific toxin, in: Pathogenesis and Mechanism of Liver Cell Necrosis, p. 163. Ed. D. Keppler. MTP Press, Lancaster 1975.

    Chapter  Google Scholar 

  9. Iwu, M.M. Antihepatotoxicity of Biflavonoid ofGarcinia kola Heckel. Proceedings of 32nd Annual Congress for Medicinal Plant Research, Antwerp 1984;Farmaceutisch Tijdschrift Voor Belgie 61 (1984), 248.

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Authors and Affiliations

  1. Phytotherapy Research Laboratory, Department of Pharmacognosy, University of Nigeria, Nsukka, Nigeria

    M. M. Iwu

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  1. M. M. Iwu
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Iwu, M.M. Antihepatoxic constituents ofGarcinia kola seeds. Experientia 41, 699–700 (1985). https://doi.org/10.1007/BF02007729

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  • DOI: https://doi.org/10.1007/BF02007729

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