Abstract
Abstract
Children born prematurely and recruited into a prospective follow up study were examined at 5 years of age. Our aim was to determine actiological associations of respiratory symptoms in such children and in particular, to determine the importance of severe chronic lung disease (CLD, oxygen dependence beyond 36 weeks post conceptional age). Respiratory status was documented from parental history in 103 children of median gestational age 29 weeks (range 23–35), 17 of whom had suffered from severe CLD. In 90 of the 103 children lung function had been assessed at 1 year of age. Regression analysis revealed that neither severe CLD nor other perinatal variables, but only a family history of atopy, significantly related to a positive symptom status. A high airways resistance at 1 year also significantly related to positive symptom status.
Conclusion
Reduction in severe CLD (oxygen dependence beyond 36 weeks postconceptional age) may make relatively little impact on respiratory morbidity in young school children born prematurely.
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Abbreviations
- BPD :
-
bronchopulmonary dysplasia
- CLD :
-
chronic lung disease
- Raw :
-
airways resistance
- TGV :
-
thoracic gas volume
- SGaw :
-
specific conductance
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Greenough, A., Giffin, F.J., Yuksel, B. et al. Respiratory morbidity in young school children born prematurelychronic lung disease is not a risk factor?. Eur J Pediatr 155, 823–826 (1996). https://doi.org/10.1007/BF02002916
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DOI: https://doi.org/10.1007/BF02002916