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Changes in ovarian function after tubal sterilization

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Advances in Contraception

Abstract

Changes in ovarian function were evaluated in 43 women, before and after tubal ligation. Midluteal endocrine profiles and endometrial biopsies were investigated before and at 3, 6 and 12 months after the operations. During postoperative follow-up there was significant increase in luteal phase deficiency and midluteal FSH, LH and E2 levels (p<0.001). Progesterone levels significantly decreased (p<0.001) and anovulation was observed in 13 (30.2%) of 43 cases. Our data suggest that tubal sterilization carried increased risk in ovarian function, particularly luteal phase deficiency and anovulation.

Resumé

Les modifications de al fonction ovarienne ont été évaluées chez 43 femmes, avant et après la ligature des trompes. Des profils endocriniens midluténiques et des biopsies de l'endomètre ont été étudiés avant l'intervention et 3, 6 et 12 mois après. Durant la période de suivi postopératoire, on a constaté une augmentation significative de carence au cours de la phase lutéle et des niveaux de l'hormone folliculostimulante, de l'hormone lunéinisante et de E2 au milieu de la phase lutéale (p<0,001). Les niveaux de progestérone ont significativement baissé (p<0.001) et l'absence d'ovulation a été observée chez 13 (30,2%) des 43 cas. Nos résultats laissent penser que la stérilisation tubaire présente un risque accru pour la fonction ovarienne, notamment une carence dans la phase lutéale et l'anovulation.

Resumen

Las modificaciones de la función ovárica se evaluaron en 43 mujeres, antes y después de ligarse las trompas. Se investigaron los perfiles en la mitad de la fase lútea y las biopsias del endometrio antes de la intervención y a los 3, 6 y 12 meses posteriores. Durante el período de seguimiento postoperatorio, se verificó un aumento significativo de carencia en el curso de la fase lútea y de los niveles de la hormona foliculoestimulante, la hormona luteinizante y E2 en la mitad de la fase lútea (p<0,001). Los niveles de progesterona disminuyeron significativamente (p<0,001) y se observó falta de ovulación en 13 (30,2%) de los 43 casos. Nuestros resultados hacen pensar que la esterilización de las trompas presenta un riesgo mayor para la función ovárica, en particular, carencia en la fase lútea y anovulación.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Dicle University, Medical Faculty, Diyarbakir, Turkey

    A. U. Hakverdi, C. E. Taner & A. C. Erden

  2. Department of Biostatistics, Dicle University, Medical Faculty, Diyarbakir, Turkey

    Ö. Satici

Authors
  1. A. U. Hakverdi
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  2. C. E. Taner
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  3. A. C. Erden
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  4. Ö. Satici
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Hakverdi, A.U., Taner, C.E., Erden, A.C. et al. Changes in ovarian function after tubal sterilization. Adv Contracept 10, 51–56 (1994). https://doi.org/10.1007/BF01986530

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  • DOI: https://doi.org/10.1007/BF01986530

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