Skip to main content
SpringerLink
Log in

Multiple control of inflammation by glucocorticoids

  • Corticosteroid Actions in Infalmmation
  • Published:
Agents and Actions Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. A. Danon andG. Assouline,Inhibition of prostaglandin biosynthesis by corticosteroids requires RNA and protein synthesis, Nature273, 552–554 (1978).

    PubMed  Google Scholar 

  2. M. Di Rosa andP. Persico,Mechanism of inhibition of prostaglandin biosynthesis by hydrocortisone in rat leucocytes, Br. J. Pharmacol.66, 161–163 (1979).

    PubMed  Google Scholar 

  3. R. Carnuccio, M. Di Rosa andP. Persico,Hydrocortisone induced inhibitor of prostaglandin biosynthesis in rat leucocytes, Br. J. Pharmacol.68, 14–16 (1980).

    PubMed  Google Scholar 

  4. G.J. Blackwell, R. Carnuccio, M. Di Rosa, R.J. Flower, L. Parente andP. Persico,Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids, Nature287, 147–149 (1980).

    Article  PubMed  Google Scholar 

  5. F. Hirata, E. Schiffman, K. Venkatasubramanian, D. Salomon andJ. Axelrod,A phospholipase A 2 inhibitory protein in rabbit neutrophils induced by glucocorticoids, Proc. natn. Acad. Sci. USA77, 2533–2536 (1980).

    Google Scholar 

  6. J.F. Cloix, O. Colard, B. Rothhut andF. Russo-Marie,Characterization and partial purification of ‘renocortins’: two polypeptides formed in renal cells causing the anti-phospholipase-like action of glucocorticoids, Br. J. Pharmacol.79, 313–321 (1983).

    PubMed  Google Scholar 

  7. G.J. Blackwell, R. Carnuccio, M. Di Rosa, R.J. Flower, C.S.J. Langham, L. Parente, P. Persico, N.C. Russel-Smith andD. Stone,Glucocorticoids induce the formation and release of anti-inflammatory and anti-phospholipase proteins into the peritoneal cavity of the rat, Br. J. Pharmacol.76, 185–194 (1982).

    PubMed  Google Scholar 

  8. F. Hirata, M. Notsu, M. Iwata, L. Parente, M. Di Rosa andR.J. Flower,Identification of several species of phospholipase inhibitory proteins by radio-immunoassay for lipomodulin, Biochem. biophys. Res. Commun.109, 223–230 (1982).

    Article  PubMed  Google Scholar 

  9. P. Coote, M. Di Rosa, R.J. Flower, L. Parente, M. Merrett andJ.N. Wood,Detection and isolation of a steroid-induced anti-phospholipase protein of high molecular weight, Br. J. Pharmacol.80, 597P (1983).

  10. B. Rothhut, F. Russo-Marie, J. Wood, M. Di Rosa andR.J. Flower,Further characterization of the glucocorticoid-induced anti-phospholipase protein ‘renocortin’, Biochem. biophys. Res. Commun.117, 878–884 (1983).

    Article  PubMed  Google Scholar 

  11. M. Di Rosa, R.J. Flower, F. Hirata, L. Parente andF. Russo-Marie,Antiphospholipase proteins, Prostaglandins28, 441–442 (1984).

    Article  PubMed  Google Scholar 

  12. G.J. Blackwell, R. Carnuccio, M. Di Rosa, R.J. Flower, J. Ivanyi, C.S. Langham, L. Parente, P. Persico andJ. Wood,Suppression of arachidonate oxidation by glucocorticoid-induced anti-phospholipase peptides, Adv. Prost. Thromb. Leukotr. Res.11, 65–71 (1983).

    Google Scholar 

  13. L. Parente, M. Di Rosa, R.J. Flower, P. Ghiara, R. Meli, P. Persico, J.A. Salmon andJ.N. Wood,Relationship between the anti-phospholipase and anti-inflammatory effect of glucocorticoid-induced proteins, Eur. J. Pharmac.99, 233–239 (1984).

    Article  Google Scholar 

  14. T. Hattori, T. Hoffman andF. Hirata,Differentiation of a histiocytic lymphoma cell line by lipomodulin, a phospholipase inhibitory protein, Biochem. biophys. Res. Commun.111, 551–559 (1983).

    Article  PubMed  Google Scholar 

  15. T. Uede, F. Hirata, M. Hirashima andK. Ishizaka,Modulation of the biological activities of IgE-binding factor, I. Identification of glycosilation-inhibiting factor as a fragment of lipomodulin, J. Immunol.130, 878–884 (1983).

    PubMed  Google Scholar 

  16. M. Koltai, I. Lepran, G.Y. Nemecz andL. Szekeres,The possible mechanism of protection by dexamethasone against sudden death due to coronary ligation in conscious rats, Br. J. Pharmac.79, 327–329 (1983).

    Google Scholar 

  17. F. Hirata, R. Del Carmine, C.A. Nelson, J. Axelrod, E. Schiffmann, A. Warabi et al.,Presence of autoantibody for phospholipase inhibitory protein lipomodulin, in patients with rheumatic diseases, Proc. natn. Acad. Sci. USA78, 3190–3194 (1981).

    Google Scholar 

  18. G. Ciabattoni, P. Patrignani, P. Filabozzi, A. Pierucci, B. Simonetti, G.A. Cinotti, E. Pinca, E. Gotti, G. Remuzzi andC. Patrono,Increased renal thromboxane (TX) production in systemic lupus erythematosus (SLE), Clin. Res.30, 445A (1982).

    Google Scholar 

  19. A. Calignano, R. Carnuccio, M. Di Rosa, A. Ialenti andS. Moncada,The anti-inflammatory effect of glucocorticoid-induced phospholipase inhibitory proteins, Agents and Actions16, 60–62 (1985).

    PubMed  Google Scholar 

  20. M. Di Rosa andD.A. Willoughby,Screens for anti-inflammatory drugs, J. Pharm. Pharmac.23, 297–298 (1971).

    Google Scholar 

  21. Y. Ōyanagui,Steroid-like anti-inflammatory effect of superoxide dismutase in serotonin, histamine, and kinin-induced oedemata of mice, Existence of vascular permeability regulating proteins(s), Biochem. Pharmac.30, 1791–1798 (1981).

    Article  Google Scholar 

  22. Y. Ōyanagui,Anti-inflammatory effects of polyamines in serotonin and carrageenin paw oedemata—possible mechanism to increase vascular permeability inhibitory protein level which is regulated by glucocorticoids and superoxide radical, Agents and Actions14, 81–89 (1984).

    Google Scholar 

  23. A.H. Janoski, J.C. Shaver, N.P. Christy andW. Rosner,On the pharmacologic actions of 21-carbon hormonal steroids (‘glucocorticoids’) of the adrenal cortex in mammals, Handb. of Expt. Pharmacol.14/3, 256–368 (1968).

    Google Scholar 

  24. E.R. Ramey andM.S. Goldstein,The adrenal cortex and the sympathetic nervous system, Physiol. Rev.37, 155–195 (1957).

    PubMed  Google Scholar 

  25. I. Fritz andR. Levine,Action of adrenal cortical steroids and nor-epinephrine on vascular responses of stress in adrenalectomized rats, Am. J. Physiol.165, 456–465 (1951).

    PubMed  Google Scholar 

  26. B.W. Zweifach, E. Shorr andM.M. Black,The influence of the adrenal cortex on behavior of terminal vascular bed, Ann. N.Y. Acad. Sci.56, 626–633 (1953).

    PubMed  Google Scholar 

  27. J. Lecompte, J. Grevisse andM.L. Beaumariage,Potentiation par l'hydrocortisone des effects moteurs de l'adrenaline, Arch. int. Pharmacodyn.119, 133–141 (1959).

    PubMed  Google Scholar 

  28. J.C. Besse andA.D. Bass,Potentiation by hydrocortisone of responses to catecholamines in vascular smooth muscle, J. Pharm. Exptl. Ther.154, 224–238 (1966).

    Google Scholar 

  29. S. Kalsner,Steroid potentiation of responses to sympathomimetic amines in aortic strips, Br. J. Pharmac.36, 582–593 (1969).

    Google Scholar 

  30. B.M. Altura,Role of glucocorticoids in local regulation of blood flow, Am. J. Physiol.211, 1393–1397 (1966).

    PubMed  Google Scholar 

  31. J. Friedland, C. Setton andE. Silverstein,Angiotensin Converting Enzyme: induction by Steroids in Rabbit Alveolar Macrophages in Culture, Science197, 64–65 (1977).

    PubMed  Google Scholar 

  32. F.A.O. Mendelsohn, C.J. Lloyd, C. Kachel andJ.W. Funder,Induction by Glucocorticoids of Angiotensin Converting Enzyme Production from Bovine Endothelial Cells in Culture and Rat Lung in vivo, J. Clin. Invest.70, 684–692 (1982).

    PubMed  Google Scholar 

  33. K.K.F. Ng andJ.R. Vane,The conversion of angiotensin I to Angiotensin II, Nature126, 762–766 (1967).

    Google Scholar 

  34. Y.S. Bakhle, A.M. Reynard andJ.R. Vane,Metabolism of the Angiotensins in Isolated Perfused Tissues, Nature222, 956–959 (1969).

    Google Scholar 

  35. B.G. Zimmerman,Actions of angiotensin on adrenergic nerve endings, Fed. Proc.37, 199–202 (1978).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Experimental Pharmacology, University of Naples, Italy

    M. Di Rosa, A. Calignano, R. Carnuccio, A. Ialenti & L. Sautebin

Authors
  1. M. Di Rosa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Calignano
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Carnuccio
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. Ialenti
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. L. Sautebin
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Di Rosa, M., Calignano, A., Carnuccio, R. et al. Multiple control of inflammation by glucocorticoids. Agents and Actions 17, 284–289 (1986). https://doi.org/10.1007/BF01982621

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01982621

Keywords

Search

Navigation