Summary
The administration of phosphatidyl choline/cholesterol liposomes with entrapped N-acetyl muramyl dipeptide induced in guinea-pigs the development of delayed hypersensitivity to ovalbumin.
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References
J. Freund and K. McDermott, Proc. Soc. exp. Biol. N. Y.49, 584 (1942).
R. G. White, L. Bernstock, R. G. Johns and E. Lederer, Immunology1, 54 (1958).
R. G. White, P. Jolles, D. Samour and E. Lederer, Immunology7, 158 (1964).
D. Migliore-Samour and P. Jolles, FEBS Lett.25, 301 (1972).
A. Adam, R. Ciorbaru, J. F. Petit and E. Lederer, Proc. natl Acad. Sci. USA39, 851 (1972).
I. J. Hiu, Nature New Biol.238, 241 (1972).
S. Kotani, Y. Watanabe, T. Shimono, T. Narita, K. Kato, D. E. S. Stewart-Tuli, Kinoshita, K. Yokogogawa, S. Katawa, T. Shiba, S. Kusmumoto and Y. Tarumi, Z. Immun Forsch.147, 302 (1975).
A. Adam, F. Ellouz, R. Ciorbaru, J. F. Pettit and E. Lederer, Z. Immun Forsch.149, 341 (1975).
L. Chedid, F. Audibert, F. Lefrancier, J. Choay and E. Lederer, Proc. natl Acad. Sci.73, 2472 (1976).
A. C. Allison and G. Gregoriadis, in: Liposomes as immunological adjuvants in lymphocytes, macrophages and cancer, p. 61. Ed. G. Mathé, I. Florentin and M. C. Simmler. Springer, Berlin 1976.
T. D. Heath, D. C. Edwarda and B. E. Ryman, Biochem. Soc. Trans.4, 129 (1976).
M. Zaoral, J. Ježek, R. Straka and K. Mašek, submitted.
G. Gregoriadis, N. Siliprandi and E. Turchetto, Life Sci.20, 1773 (1977).
A. W. Segal, E. J. Wills, J. E. Richmond, G. Slavin and G. Gregoriadis, Br. J. exp. Path.55, 320 (1974).
L. Mattenberger-Kreber, L. G. Auderset, M. Schneider, A. Louis-Broillet, M. Strolin Benedetti and A. Malnoë, Experientia32, 1522 (1976).
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Mašek, K., Zaoral, M., Ježek, J. et al. Immunoadjuvant activity of synthetic N-acetyl muramyl dipeptide. Experientia 34, 1363–1364 (1978). https://doi.org/10.1007/BF01981474
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DOI: https://doi.org/10.1007/BF01981474