Summary
In the cerebellar particulate fractions from Gunn rat homozygotes 3 protein bands with apparent mol.wts of 250,000, 50,000 and 33,000 in SDS-polyacrylamide gel disc electrophoresis underwent major changes, and phototherapy of the newborns could effectively prevent the changes.
Similar content being viewed by others
References
C.K. Gunn, J. Hered.29, 137 (1938).
H.S. Schutta and L. Johnson, J. Neuropath. exp. Neurol.26, 377 (1967).
T.R.C. Sisson, S. Goldberg and B. Slaven, Pediat. Res.8, 647 (1974).
Y. Sawasaki, N. Yamada and H. Nakajima, J. Neurochem.27, 577 (1976).
H. Sato, R.K. Semba and S. Kashiwamata, Biol. Neonate32, 158 (1977).
P.E. Burba and R. Zand, Biochem. biophys. Res. Commun.58, 1142 (1974).
A. Greenfield and A.P.N. Majumdar, J. neurol. Sci.22, 83 (1974).
G.F.L. Ames, J. biol. Chem.249, 634 (1974).
O.H. Lowry, N.J. Rosebrough, A.L. Farr and R.J. Randall, J. biol. Chem.193, 265 (1951).
G. Fairbanks, T.L. Steck and D.F.H. Wallach, Biochemistry10, 2606 (1971).
J. Mallett, M. Huchet, R. Pougeois and J.P. Changeux, Brain Res.103, 291 (1976).
A. Hirano and H.M. Dembitzer, J. Neuropath. exp. Neurol.34, 1 (1975).
S.C. Landis, J. Cell Biol.57, 782 (1973).
Y. Tamaki and Y. Yamasaki, Physiol. Behav.17, 615 (1976).
Author information
Authors and Affiliations
Additional information
A part of this research was supported by grants from the Ministry of Education in Japan (No.448131) and the Japan Association for Maternal Welfare.
Rights and permissions
About this article
Cite this article
Kashiwamata, S., Aono, S. & Semba, R.K. Characteristic changes of cerebellar proteins associated with cerebellar hypoplasia in jaundiced Gunn rats and the prevention of these by phototherapy. Experientia 36, 1143–1144 (1980). https://doi.org/10.1007/BF01976089
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01976089