References
Chabrol B, Mancini J, Chretien D, Rustin P, Munnich A, Pinsard N (1994) Valproate-induced hapatic failure in a case of cytochrome c oxidase deficiency. Eur J Pediatr 153:133–135
Ponchaut S, Van Hoof F, Veitch K (1992) Cytochrome aa3 depletion is the cause of the ceficient mitochondrial respiration induced by chronic valproate administration. Biochem Pharmacol 43: 644–647
Hayasaka K, Takahashi I, Kobayashi Y Iinuma K, Narisawa K, Tada K (1986) Effects of valproate on biogenesis and function of liver mitochondria. Neurology 36:351–356
Ponchaut S, Veitch K (1993) Valproate and mitochondria. Biochem Pharmacology 46:199–204
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Ponchaut, S., Van Hoof, F. & Veitch, K. Valproate and cytochromec oxidase deficiency. Eur J Pediatr 154, 79 (1995). https://doi.org/10.1007/BF01972980
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DOI: https://doi.org/10.1007/BF01972980