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DNA-binding antibodies derived from autoimmune MRL mice fail to induce clinical changes when administered to healthy animals

  • Autoimmune Models of Tissue Destruction
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References

  1. R. A. Lake, A. Morgan, B. Henderson and N. A. Staines,A key role for fibronectin in the sequential binding of native dsDNA and monoclonal anti-DNA antibodies to components of the extracellular matrix: its possible significance in glomerulonephritis. Immunology54, 389–395 (1985).

    PubMed  Google Scholar 

  2. E. Ben Chetrit, E. H. Dunskey, S. Wollner and D. Eilat,In vivo clearence and tissue uptake of anti-DNA monoclonal antibody and its complexes with DNA. Clin. exp. Immunology60, 159–168 (1985).

    Google Scholar 

  3. A. Morgan, R. R. C. Buchanan, A. M. Lew, I. Olsen and N. A. Staines,Five groups of antigenic determinants on DNA identified by monoclonal antibodies from (NZB×NZW)F 1 and MRL/Mp-lpr/lpr mice. Immunology55, 75–83 (1985).

    PubMed  Google Scholar 

  4. B. H. Hahn and F. M. Ebling,Suppression of murine lupus nephritis by administration of an anti-idiotypic antibody to anti-DNA. J. Immunol.132, 186–190 (1983).

    Google Scholar 

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Lake, R., Staines, N. DNA-binding antibodies derived from autoimmune MRL mice fail to induce clinical changes when administered to healthy animals. Agents and Actions 19, 306–308 (1986). https://doi.org/10.1007/BF01971232

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