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Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats

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Summary

In diabetic rats,3H-estradiol binding by the cytosol and nuclei of the anterior pituitary was lower than normal. Changes in affinity and receptor numbers were demonstrated by Scatchard analysis. Protein synthesis in diabetic pituitaries, however, was in the normal range.

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Authors and Affiliations

  1. Laboratorio de Esteroides, Instituto de Biologia y Medicina Experimental, Obligado 2490, 1428, Buenos Aires, Argentina

    H. Coirini, L. Weisenberg, S. Tornello & A. F. De Nicola

Authors
  1. H. Coirini
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  2. L. Weisenberg
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  3. S. Tornello
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  4. A. F. De Nicola
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Coirini, H., Weisenberg, L., Tornello, S. et al. Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats. Experientia 36, 683–685 (1980). https://doi.org/10.1007/BF01970139

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  • DOI: https://doi.org/10.1007/BF01970139

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