Skip to main content
SpringerLink
Log in

Percutaneous penetration of indomethacin

  • Published:
Experientia Aims and scope Submit manuscript

Summary

14C-Indomethacin (ID) was applied to the skin of guinea-pigs as an ointment. After several applications, the concentration of ID in the skin and muscle under the applied site reached a constant level. The concentration of ID in the muscle as well as the skin may be enough to exert an anti-inflammatory effect.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. P. Pause, P. Zeiller and K.H. Sensh, Drug. Res.24, 1298 (1974).

    Google Scholar 

  2. H. Takahashi and K. Iwatsubo, Yakuzaigaku23, 49 (1963).

    CAS  Google Scholar 

  3. H.B. Hucker and E.A. Hoffman, J. Pharm. Sci.60, 1049 (1971).

    Article  CAS  PubMed  Google Scholar 

  4. H.W. Emori, G.D. Champion, R. Bluestone and H.E. Paulus, Ann. Rheum. Dis.32, 433 (1973).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Tokyo Research Laboratories, Kowa Co. Ltd, Higashimurayama, 189, Tokyo, Japan

    H. Ishihama, H. Kimata & Y. Mizushima

  2. The 1st Department of Internal Medicine, St. Marianna University School of Medicine, Takatsu-ku, 213, Kawasaki, Japan

    H. Ishihama, H. Kimata & Y. Mizushima

Authors
  1. H. Ishihama
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Kimata
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Y. Mizushima
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ishihama, H., Kimata, H. & Mizushima, Y. Percutaneous penetration of indomethacin. Experientia 35, 798–799 (1979). https://doi.org/10.1007/BF01968257

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01968257

Keywords

Search

Navigation