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Bombesin, calcitonin and leu-enkephalin immunoreactivity in endocrine cells of human lung

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Summary

By immunohistochemistry, bombesin, calcitonin and leu-enkephalin was localized in endocrine cells of human lungs from various age groups. It is suggested that at least 3 different peptide containing endocrine cells may be present in human lung.

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Authors and Affiliations

  1. Departments of Surgery and Clinical Biochemistry, Mt. Sinai Hospital and University of Toronto, M5G 1X8, Toronto, Ontario, Canada

    E. Cutz, W. Chan & N. S. Track

  2. Department of Pathology, The Hospital for Sick Children, 555 University Ave., M5G 1X8, Toronto, Ontario, Canada

    E. Cutz, W. Chan & N. S. Track

Authors
  1. E. Cutz
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  2. W. Chan
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  3. N. S. Track
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Additional information

Acknowledgments. The authors thank Dr Camille Vaillant, University of Liverpool, for advice with immunohistochemical methods and Dr G. Dockray for his generous gift of bombesin antiserum. This work has been supported by Medical Research Council of Canada (MA-7054) and Ontario Thoracic Society.

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Cutz, E., Chan, W. & Track, N.S. Bombesin, calcitonin and leu-enkephalin immunoreactivity in endocrine cells of human lung. Experientia 37, 765–767 (1981). https://doi.org/10.1007/BF01967969

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  • DOI: https://doi.org/10.1007/BF01967969

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