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Adrenocorticotrophic hormone and cyclic adenosine monophosphate effect on mouse adrenal cortical cell membrane potential

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Summary

Adrenocorticotrophic hormone (ACTH) and cyclic adenosine monophosphate (cAMP) both caused a rapid and transient depolarization of the resting membrane potential of superfused rat adrenal cortical cells. The membrane depolarization to both secretagogues were very similar. The membrane potential changes occurred as early as 0.1 min and were dose dependent in both onset and extent of depolarization.

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Authors and Affiliations

  1. Department of Physiology, Tulane University Medical School, 70112, New Orleans, Louisiana, USA

    J. R. Lymangrover

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  1. J. R. Lymangrover
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The author gratefully acknowledges the generous financial support of the E.G. Schlieder Educational Foundation, the American Heart Association of Louisiana and the American Heart Association.

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Lymangrover, J.R. Adrenocorticotrophic hormone and cyclic adenosine monophosphate effect on mouse adrenal cortical cell membrane potential. Experientia 36, 613–614 (1980). https://doi.org/10.1007/BF01965834

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