Skip to main content
Log in

Hormones, thymus and lymphocyte functions

  • Cogitationes
  • Published:
Experientia Aims and scope Submit manuscript

Zusammenfassung

Es wird die Hypothese vorgeschlagen, dass Thymus-Lymphozyten (T-Zellen) neben ihren klassischen immunologischen Funktionen wichtige multifunktionelle homöostatische Kontrollfunktionen ausüben. Störungen in der Beziehung zwischen dem endokrinen System und Thymus führen zu Ausfallerscheinungen und Altern.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. W. Pierpaoli, N. Fabris andE. Sorkin, inHormones and the Immune Response. Ciba Foundation Study Group. No. 36 (Eds.G. E. W. Wolstenholme andJulie Knight: Churchill, London 1970), p. 126.

    Google Scholar 

  2. W. Pierpaoli, N. Fabris andE. Sorkin, inCellular Interactions in the Immune Response (Eds.S. Cohen, G. Cudkowicz andR. T. Mc Cluskey, Karger, Basel 1971), p. 25.

    Google Scholar 

  3. N. Fabris, W. Pierpaoli andE. Sorkin, inDevelopmental Aspects of Antibody Formation and Structure (Eds.J. Sterzl andI. Riha, Czekoslovak Academy of Science, Prague, 1970), vol. 1. p. 79.

    Google Scholar 

  4. N. Fabris, W. Pierpaoli andE. Sorkin, Clin. exp. Immunol.9, 209 and 227 (1971).

    CAS  PubMed  PubMed Central  Google Scholar 

  5. W. Pierpaoli, E. Bianchi andE. Sorkin, Clin. exp. Immunol.9, 889 (1971).

    CAS  PubMed  PubMed Central  Google Scholar 

  6. E. Sorkin, W. Pierpaoli, N. Fabris andElena Bianchi, inGrowth and Growth Hormone (Eds.A. Pecile andE. E. Müller, Excerpta Medica, Amsterdam 1972), p. 132.

    Google Scholar 

  7. W. Pierpaoli andE. Sorkin, Nature, New Biol.238, 282 (1972).

    Article  CAS  PubMed  Google Scholar 

  8. W. Pierpaoli andE. Sorkin, Experientia28, 851 (1972).

    Article  CAS  PubMed  Google Scholar 

  9. J. M. Yoffey, Lancet1, 206 (1962).

    Article  CAS  PubMed  Google Scholar 

  10. J. F. Loutit, Lancet2, 1106 (1962).

    Article  Google Scholar 

  11. R. G. Burwell, Lancet2, 69 (1963).

    Article  CAS  PubMed  Google Scholar 

  12. P. R. J. Burch,Growth, Disease and Ageing (Oliver andBoyd, Edinburgh 1968).

    Google Scholar 

  13. W. S. Bullough,The Evolution of Differentiation (Academic Press, London, 1967).

    Google Scholar 

  14. W. S. Bullough, Nature229, 608 (1971).

    Article  CAS  PubMed  Google Scholar 

  15. N. Fabris, W. Pierpaoli andE. Sorkin, Nature, Lond., in press.

  16. D. M. V. Parrott, Transplant. Bull.29, 102 (1962).

    Article  CAS  Google Scholar 

  17. J. F. A. P. Miller, Ann. N.Y. Acad. Sci.99, 340 (1962).

    Article  Google Scholar 

  18. D. M. V. Parrott andJ. East, Nature, Lond.195, 347 (1962).

    Article  CAS  PubMed  Google Scholar 

  19. D. M. V. Parrott andJ. East, inThe Thymus in Immunobiology (Eds.R. A. Good andA. E. Gabrielsen; Hoeber-Harper, New York 1964), p. 523.

    Google Scholar 

  20. J. F. A. P. Miller andP. Dukor,Die Biologie des Thymus nach dem heutigen Stand der Forschung (Karger, Basel 1964).

    Google Scholar 

  21. K. R. Mc Intire, S. Sell andJ. F. A. P. Miller, Nature, Lond.204, 151 (1964).

    Article  Google Scholar 

  22. M. W. Hess, H. Cottier andR. D. Stoner, J. Immunol.91, 425 (1963).

    Article  CAS  PubMed  Google Scholar 

  23. R. Wilson, K. Sjodin andM. Bealmar, Proc. Soc. exp. Biol. Med.117, 237 (1964).

    Article  CAS  PubMed  Google Scholar 

  24. H. A. Azar, J. Williams andK. Takatsuki, inThe Thymus, (Eds.V. Defendi andD. Metcalf; The Wistar Institute Press, Philadelphia 1964), p. 75.

    Google Scholar 

  25. J. East, D. M. V. Parrott, F. C. Chesterman andA. Pomerance, J. exp. Med.118, 1069 (1963).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. L. W. Law, Cancer Res.26, 551 (1966).

    CAS  PubMed  Google Scholar 

  27. J. Szeri, Zs. Bános, P. Anderlik, M. Balázs andP. Földes, Acta microbiol. hung.13, 255 (1966).

    CAS  Google Scholar 

  28. P. J. Porter, A. R. Spievack andE. H. Kass, J. Lab. clin. Med.68, 455 (1966).

    CAS  PubMed  Google Scholar 

  29. D. Keast, Immunology15, 237 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  30. D. Keast andM. N.-I. Walters, Immunology15, 247 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  31. M. W. Hess,Experimental Thymectomy, Possibilities and Limitations (Springer Verlag, Berlin, 1968).

    Book  Google Scholar 

  32. E. Bianchi, W. Pierpaoli andE. Sorkin, J. Endocrin.51, 1 (1971).

    Article  CAS  Google Scholar 

  33. R. E. Billingham,The Biology of Graft-Versus-Host Reactions, The Harvey Lectures, series 62 (Academic Press, New York 1968), p. 21.

    Google Scholar 

  34. W. Pierpaoli andE. Sorkin, Nature, Lond.215, 834 (1967).

    Article  Google Scholar 

  35. W. Pierpaoli andE. Sorkin, inThe Immune Response and its Suppression. Antibiotica et Chemotherapia15 (Ed.E. Sorkin, Karger, Basel 1969), p. 122.

    Google Scholar 

  36. W. Pierpaoli, C. Baroni, N. Fabris andE. Sorkin, Immunology16, 217 (1969).

    CAS  PubMed  PubMed Central  Google Scholar 

  37. W. Pierpaoli andE. Sorkin, inLymphatic Tissue and Germinal Centers in Immune Response (Eds.L. Fiore-Donati andM. G. Hanna Jr.; Plenum Press, New York, 1969).

    Google Scholar 

  38. L. W. Law, T. B. Dunn, N. Trainin andR. H. Levey, inThe Thymus (Eds.V. Defendi andD. Metcalf, The Wistar Institute Press, Philadelphia, 1964), p. 105.

    Google Scholar 

  39. M. Simonsen, Progr. Allergy6, 349 (1962).

    CAS  Google Scholar 

  40. C. C. Rust, Gen. comp. Endocrin.5, 222 (1965).

    Article  CAS  Google Scholar 

  41. C. D. Turner,General Endocrinology, 4th edn. (Saunders, Philadelphia 1966), p. 123.

    Google Scholar 

  42. H. Balner andH. Dersjant, Nature, Lond.209, 815 (1966).

    Article  CAS  PubMed  Google Scholar 

  43. J. D. Sherman, M. M. Adner andW. Damashek, Blood22, 252 (1963).

    Article  CAS  PubMed  Google Scholar 

  44. Y. Nishizuka andT. Sakakura, Science166, 753 (1969).

    Article  CAS  PubMed  Google Scholar 

  45. H. S. Micklem andJ. F. Loutit,Tissue Grafting and Radiation (Academic Press, New York 1966).

    Google Scholar 

  46. M. S. Brook J. exp. Med.120, 375 (1964).

    Article  Google Scholar 

  47. R. D. Ekstedt andE. T. Nishimura, J. exp. Med.120, 795 (1964).

    Article  PubMed Central  Google Scholar 

  48. L. Berek, Zs. Bános, I. Szeri, P. Anderlik andK. Aszodi, Experientia24, 721 (1968).

    Article  CAS  PubMed  Google Scholar 

  49. L. Berek, Experientia25, 633 (1969).

    Article  CAS  PubMed  Google Scholar 

  50. L. Berek, K. Aszodi, Zs. Bános, P. Anderlik andI. Szeri, Experientia25, 982 (1969).

    Article  CAS  PubMed  Google Scholar 

  51. L. Berek, K. Gefferth, Zs. Bános, P. Anderlik, I. Szeri andK. Aszodi, Acta paediat. hung.11, 51 (1970).

    CAS  Google Scholar 

  52. M. Vendeputte andP. De Somer, J. natn. Cancer Inst.,35, 237 (1965).

    Google Scholar 

  53. P. Grabar, personal communication.

  54. W. Pierpaoli, personal observations.

  55. M. Schlesinger andR. Mark, Science143, 965 (1964).

    Article  CAS  PubMed  Google Scholar 

  56. N. D. Reed andJ. W. Jutila, J. Immunol.99, 238 (1967).

    Article  CAS  PubMed  Google Scholar 

  57. J. D. Sherman andW. Damesilek, inThe Thymus in Immunobiology (Eds.R. A. Good andA. E. Gabrielsen, Harper and Row, New York 1964), p. 542.

    Google Scholar 

  58. R. W. Reilly, J. S. Thompson, R. K. Bielski andC. D. Severson, J. Immunol.98 231 (1967).

    Article  Google Scholar 

  59. A. P. Monaco, M. L. Wood, J. G. Gray andP. S. Russel, J. Immunol.96, 229 (1966).

    Article  CAS  PubMed  Google Scholar 

  60. R. L. Walford, inThe Immunologic Theory of Aging (Munksgaard, Copenhagen 1969), p. 135.

    Google Scholar 

  61. D. Metcalf, R. Moulds andB. Pike, Clin. exp. Immunol.2, 109 (1966).

    Google Scholar 

  62. W. Pierpaoli andE. Sorkin, Immunology16, 311 (1969).

    CAS  PubMed  PubMed Central  Google Scholar 

  63. W. Pierpaoli, N. Fabris andE. Sorkin, unpublished experiments.

  64. S. P. Flanagan, Genet. Res.8, 295 (1966).

    Article  CAS  PubMed  Google Scholar 

  65. E. M. Pantelouris, Nature, Lond.217, 370 (1968).

    Article  CAS  PubMed  Google Scholar 

  66. W. Pierpaoli andE. Sorkin, Br. J. exp. Path.48, 627 (1967).

    CAS  Google Scholar 

  67. W. Pierpaoli andE. Sorkin, J. Immunol.101, 1036 (1968).

    Article  CAS  PubMed  Google Scholar 

  68. F. M. Burnet, Lancet2, 358 (1970).

    Article  CAS  PubMed  Google Scholar 

  69. J. F. A. P. Miller, Nature, Lond.195, 1318 (1962).

    Article  Google Scholar 

  70. A. M. Cross, E. Leuchars andJ. F. A. P. Miller, J. exp. Med.119, 837 (1964).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  71. J. F. A. P. Miller, A. H. E. Marshall andR. G. White, Adv. Immunol.2, 111 (1962).

    Article  CAS  Google Scholar 

  72. J. F. A. P. Miller, Proc. R. Soc. London156, 415 (1962).

    Google Scholar 

  73. J. F. A. P. Miller, Science144, 1544 (1964).

    Article  CAS  PubMed  Google Scholar 

  74. L. Gitman,Endocrines and Aging (Thomas, Springfield 1967).

    Google Scholar 

  75. H. D. Moon, C. H. Li andM. E. Simpson, Cancer Res.16, 111 (1956).

    CAS  PubMed  Google Scholar 

  76. S. M. Glick, J. Roth, R. S. Yalow andS. A. Berson, Recent Progr. Horm. Res.21, 241 (1965).

    CAS  PubMed  Google Scholar 

  77. F. C. Greenwood andJ. Landon, Nature, Lond.210, 540 (1966).

    Article  CAS  PubMed  Google Scholar 

  78. D. S. Schlach, J. Lab. clin. Med.69, 256 (1967).

    Google Scholar 

  79. E. M. Baylis, F. Greenwood, V. James, J. Jenkins, J. Landon, V. Marks andE. Samols, inGrowth Hormone (Eds.A. Pecile andE. Müller, Excerpta Medica Foundation, Amsterdam 1968), p. 89.

    Google Scholar 

  80. D. S. Schalch andS. Reichlin, inGrowth Hormone (Eds.A. Pecile andE. Müller, Excerpta Medica Foundation, Amsterdam 1968), p. 211.

    Google Scholar 

  81. C. Desjardins, K. T. Kirton andH. D. Hafs, Proc. Soc. exp. Biol. Med.126, 23 (1967).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Acknowledgement. This work was supported by the Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung, Grant No. 3.246.69 SR, and theEmil-Barell-Stiftung, Basel.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pierpaoli, W., Sorkin, E. Hormones, thymus and lymphocyte functions. Experientia 28, 1385–1389 (1972). https://doi.org/10.1007/BF01965362

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01965362

Keywords

Navigation