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Leydig cell function in streptozotocin-induced diabetic rats

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Summary

Streptozotocin diabetic rats were infertile as a result of decreased Leydig cell function of the testes. The major changes found were: decreased number of Leydig cells and their spontaneous secretion of testosterone. No change in the receptors to LH on the Leydig cells was observed. LH was found to be obligatory for the regulation of Leydig cell function and fertility.

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Authors and Affiliations

  1. Soferman Institute for the Study of Fertility, Maternity Hospital, P.O.B. 7079, Tel-Aviv, Israel

    G. Paz & Z. T. Homonnai

Authors
  1. G. Paz
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  2. Z. T. Homonnai
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Paz, G., Homonnai, Z.T. Leydig cell function in streptozotocin-induced diabetic rats. Experientia 35, 1412–1413 (1979). https://doi.org/10.1007/BF01964042

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  • DOI: https://doi.org/10.1007/BF01964042

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