Summary
A correlation between the postirradiation increase of the small intestine motility and the prostaglandin-like activity in this organ during gastrointestinal syndrome was observed. Indomethacin decreased the elevated motility of intestine and reduced the prostaglandin-like activity in this syndrome.
Similar content being viewed by others
References
S.R. Gould, Prostaglandins11, 489 (1976).
P.K. Moore, J.R.S. Hoult and A.S. Laurie, Lancet2, 98 (1978).
P. Sharon, M. Ligumsky, D. Rachmilewitz and U. Zor, Gastroenterology75, 638 (1978).
E.D. Williams, S.M.M. Karim and M. Sandler, Lancet1, 22 (1968).
A. Bennett, Nature231, 536 (1971).
R.K. Farris, E.J. Tapper, D.W. Powell and S.M. Morris, J. clin. Invest.57, 916 (1976).
J.J. Misiewicz, S.L. Waller, N. Kiley and E.W. Horton, Lancet1, 648 (1969).
A. Robert, in: Advances in Prostaglandin and Thromboxane Research, p. 507. Ed. B. Samuelsson and R. Paoletti, New York 1976.
E. Beubler and H. Juan, Experientia34, 386 (1978).
G.B. Gerber and K.I. Altman, in Radiation Biochemistry, vol. 2, p. 2. Ed. G.B. Gerber, K.I. Altman and S. Okada. Academic Press, New York and London 1970.
S. Lowe and G. Faure, Naunyn-Schmiedebergs Arch. Pharmak.107, 271 (1925).
J.R. Vane, Nature, New Biol.231, 232 (1971).
W.G. Unger, I.F. Stamford and A. Bennett, Nature233, 336 (1971).
J.R. Vane, Br. J. Pharmac. Chemother.12, 344 (1957).
A. Gilmore and J.R. Vane, Nature218, 1135 (1968).
V. Eisen and D.I. Walker, Br. J. Pharmac.62, 461P (1978).
V. Eisen and D.I. Walker, Br. J. Pharmac.57, 527 (1976).
V. Eisen and D.I. Walker, S.G. Binysh and R.S. Tedder, Agents Actions, suppl. 2, p. 99 (1977).
A.T. Mennie, V.M. Dalley, L.C. Dinneen and H.O.J. Collier, Lancet2, 942 (1975).
Author information
Authors and Affiliations
Additional information
Acknowledgments. The work was supported by the Polish Academy of Sciences.
Rights and permissions
About this article
Cite this article
Borowska, A., Sierakowski, S., Maćkowiak, J. et al. A prostaglandin-like activity in small intestine and postirradiation gastrointestinal syndrome. Experientia 35, 1368–1370 (1979). https://doi.org/10.1007/BF01964014
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01964014