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Age-related lipid peroxidation in the digestive gland of mussels: The role of the antioxidant defence systems

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Summary

The main cellular defence systems against free radical-mediated oxidative stress are significantly reduced in the dige+ive gland of aged (>10 years old) compared to younger (2–4 years old) mussels (Mytilus edulis L.). Moreover, the concentration of lipid peroxidation products (malondialdehyde) is increased in the same age group with respect to younger animals. The obtained data indicate that an impairment of the antioxidant defence systems would render the older animals more susceptible to peroxidative stress, thus supporting the general significance of the free radical theory of aging.

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References

  1. Hayflick, L., Exp. Geront.20 (1985) 145

    Article  CAS  Google Scholar 

  2. Harman, D., Proc. natl Acad. Sci. USA78 (1981) 7124.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Reiss, U., and Gershon, D., Biochem. biophys. Res. Commun.73 (1976) 255.

    Article  CAS  PubMed  Google Scholar 

  4. Stege, T. E., Mischke, B. S., and Zipperer, W. C., Exp. Geront17 (1982) 273.

    Article  CAS  Google Scholar 

  5. Videla, L. A., Fernandez, V., and Valenzuela, A., Cell Biochem. Funct.5 (1987) 273.

    Article  CAS  PubMed  Google Scholar 

  6. Rikans, L. E., and Moore, D. R., Biochem. biophys. Acta966 (1988) 269.

    Article  CAS  PubMed  Google Scholar 

  7. Bayne, B. L., Marine Mussels: Their Ecology and Physiology. Ed. B. L. Bayne. Cambridge University Press 1976.

  8. Kappus, H., and Sies, H., Experientia37 (1981) 1233

    Article  CAS  PubMed  Google Scholar 

  9. Jones, D. P., in: Oxidative stress, p. 151. Ed. H. Sies. Academic Press. New York 1985.

    Chapter  Google Scholar 

  10. Winston, G. W., Livingstone, D. R., and Lips, F., J. exp. Zool. (1990) in press.

  11. Livingstone, D. R., Garcia Martinez, P., and Winston, G. W., Aquat. Toxic.15 (1989) 213.

    Article  CAS  Google Scholar 

  12. Garcia Martinez, P., O'Hara, S., Winston, G. W., and Livingstone, D. R., Mar. Envir. Res. (1990) in press.

  13. Bus, J. S., and Gibson, J. E., Rev. Biochem. Toxic. (1979) 125.

  14. McCord, J. M., Rev. Biochem. Toxic. (1979) 109.

  15. Ursini, F., and Bindoli, A., Analyt. Biochem.44 (1987) 255.

    CAS  Google Scholar 

  16. Hissin, P. J., and Hilf, R., Analyt. Biochem.74 (1976) 214.

    Article  CAS  PubMed  Google Scholar 

  17. Esterbauer, H., Lang, J., Zadravec, S., and Slater, T., Meth. Enzym.105 (1984) 319.

    Article  CAS  PubMed  Google Scholar 

  18. Viarengo, A., Canesi, L., Pertica, M., Poli, G., Moore, M. N., and Orunesu, M., Comp. Biochem. Physiol.97C (1990) 37.

    CAS  Google Scholar 

  19. Burton, k., Webb, A., and Ingold, K. V., Lipids20 (1985) 6049.

    Article  Google Scholar 

  20. Campbell, S. A., Mar. Biol.4 (1969) 227.

    Article  CAS  Google Scholar 

  21. Burton, K., Biochem. J.62 (1956) 315.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. McCord, J. M., and Fridovich, I., J. biol. Chem.244 (1969) 6049.

    Article  CAS  PubMed  Google Scholar 

  23. Gunzler, W. A., and Flohé, L., in: Handbook Methods for Oxygen Radical Research, p. 285. Ed. R. A. Greenwald. CRC press, Boca Raton, Florida 1985.

    Google Scholar 

  24. Viarengo, A., Canesi, L., Pertica, M., and Orunesu, M., Atti Riunione congiunta SIBS, SIF, SINU, Taormina 1989.

  25. Tollefsbol, T. O., and Cohen, H. J., Exp. Geront.21 (1986) 129.

    Article  CAS  Google Scholar 

  26. Goldberg, E. D., Bowen, V. T., Farrington, J. W., Harvey, G., Martin, J. H., Parker, P. L., Risebrough, R. W., Robertson, W., Schneider, E., and Gamble, E., Envir. Conserv.5 (1978) 101.

    Article  CAS  Google Scholar 

  27. Slater, T. F., Biochem. J.222 (1984) 1.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Istituto di Fisiologia Generale, Università di Genova, Corso Europa 26, I-16132, Genova, Italy

    A. Viarengo, L. Canesi, D. R. Livingstone & M. Orunesu

  2. Plymouth Marine Laboratory, Citadel Hill, PL1 2PB, Plymouth, England

    M. Pertica

Authors
  1. A. Viarengo
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  2. L. Canesi
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  3. M. Pertica
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  4. D. R. Livingstone
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  5. M. Orunesu
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Viarengo, A., Canesi, L., Pertica, M. et al. Age-related lipid peroxidation in the digestive gland of mussels: The role of the antioxidant defence systems. Experientia 47, 454–457 (1991). https://doi.org/10.1007/BF01959942

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  • DOI: https://doi.org/10.1007/BF01959942

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