Abstract
A 22-year-old man with chronic mucocutaneous candidiasis (CMC) and hypothyroidism developed severe bronchiectases following recurrent bronchopneumonia. Immunological investigations revealed IgG2/IgG4 subclass deficiency and absence of antibodies against pneumococcal and Haemophilus polysaccharides. Under regular immunoglobulin substitution every 3 weeks pulmonary symptoms improved markedly.
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Abbreviations
- CA:
-
Candida albicans
- CMC:
-
chronic mucocutaneous candidiasis
- HIB:
-
Haemophilus influenzae type B
References
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Brägger, C., Seger, R.A., Aeppli, R. et al. IgG2/IgG4 subclass deficiency in a patient with chronic mucocutaneous candidiasis and bronchiectases. Eur J Pediatr 149, 168–169 (1989). https://doi.org/10.1007/BF01958272
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DOI: https://doi.org/10.1007/BF01958272