Summary
As reported previously, fluorescent granular perithelial cells (F.G.P.) are distributed along small blood vessels, possibly postcapillary venous vessels, in the cerebral cortex; these cells take up intraventricularly administered horseradish peroxidase efficiently. In this study it is shown that lipid substances of the blood are easily incorporated into F.G.P. and stored in their cytoplasm. The quantity of fat deposits in F.G.P. varies with the age of the animal and is very marked in old rats. The administration of elastase suppresses the fat uptake and/or facilitates the fat metabolism in F.G.P.
References
Mato, M., Ookawara, S., Tooyama, K., and Ishizaki, T., Experientia37 (1981) 1013.
Westergaard, E., and Brightman, M.W., J. comp. Neurol.152 (1973) 17.
Mato, M., and Ookawara, S., Am. J. Anat.162 (1981) 45.
Baló, J., and Banga, I., Acta physiol. hung.4 (1953) 187.
Author information
Authors and Affiliations
Additional information
Acknowledgment. This study was supported in part by a grant in aid for Scientific Research from the Ministry of Education of Japan (No. 448085). The authors also would like to express their hearty thanks to Eisai Co. for a supply of elastase.
Rights and permissions
About this article
Cite this article
Mato, M., Ookawara, S., Sano, M. et al. Uptake of fat by fluorescent granular perithelial cells in cerebral cortex after administration of fat rich chow. Experientia 38, 1496–1498 (1982). https://doi.org/10.1007/BF01955791
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01955791