Abstract
We report a rare case of congenital mumps infection in a newborn girl. Her mother developed bilateral parotitis beginning the day of the delivery. The child was subsequently severely ill and suffered from fever, splenomegaly and thrombocytopenia, however, without parotitis nor pancreatic involvement. Both mother and child recovered well with symptomatic treatment. A review of the literature shows that clinical mumps is rare and usually benign in neonates. However, severe respiratory distress may occur. The recent appearance of mumps outbreaks in adolescents and young adults calls for a reinforcement of mumps vaccination and should prompt an immunological assessment of pregnant women after exposure.
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Abbreviations
- MMR:
-
Mumps, measles, rubella vaccine
References
Aase JM, Noren GR, Venudhar Reddy D, St Geme JW (1972) Mumps-virus infection in pregnant women and the immunologic response of their offspring. N Engl J Med 286:1379–1382
Bakshi SS, Cooper LZ (1990) Rubella and mumps vaccines. Pediatr Clin N Am 37:651–668
Finland M (1973) Mumps. In: Charles D, Finland M (eds) Obstetrics and perinatal infections. Lea and Febiger, Philadelphia, pp 333–353
Gershon AA (1990) Chickenpox, measles and mumps. In: Remington JS, Klein JO (eds) Infectious diseases of the fetus and newborn infant. W. B. Saunders, Philadelphia pp 395–445
Groenendaal F, Rothbarth PH, Anker JN van den, Spritzer R (1990) Congenital mumps pneumonia: a rare cause of neonatal respiratory distress. Acta Pediatr Scand 79:1252–1254
Harris RW, Turnball CD, Isacson P, et al (1968) Mumps in the Northeast metropolitan community. I. Epidemiology of clinical mumps. Am J Epidemiol 88:224–230
Hersh BS, Fine PE, Kay Kent W, et al (1991) Mumps outbreak in a highly vaccinated population. J Pediatr 119:187–193
Homans (1855) Mumps in a pregnant woman. Premature labour, followed by the appearance of the same disease in the infant, twenty-four hours after its birth. Am J Med Sci 29:56
Hyatt HW (1961) Relationship of maternal mumps to congenital defects and fetal deaths, and to maternal morbidity and mortality. Am Pract Dig Treat 12:359–363
Jones JF, Ray CG, Fulginiti VA (1980) Perinatal mumps infection. J Pediatr 96:912–914
Kaplan KM, Marder DC, Cochi SL, Prebuld SR (1988) Mumps in the workplace, further evidence of the changing epidemiology of a childhood vaccine-preventable disease. J Am Med Assoc 260:1434–1438
Korones SB (1988) Uncommon virus infections of the mother, fetus, and newborn: Influeza, mumps and measles. Clin Perinatol 15:259–272
Monif GR (1974) Maternal mumps infection during gestation: observations on the progeny. Am J Obstet Gynecol 119:549–551
Anonymous (1990) Mumps prevention. MMWR 38:388–400
Philip RN, Reinhard KR, Lackman DB (1959) Observations on a mumps epidemic in a “virgin” population. Am J Hyg 69:91–111
Reman O, Freymuth F, Laloum D, Bonte JF (1986) Neonatal distress due to mumps. Arch Dis Child 61:80–81
Rosen A, Sternister W, Klein M (1989) Präpartale Mumps-infektion, ein Risiko für das Neugeborene? Z Geburt Perinatol 193:100–101
Sterner G, Grandien M (1990) Mumps in pregnancy at term. Scand J Infect Dis 71 [Suppl]:36–38
Zardini V (1962) Eccezionale caso di parotite epidemica in neonato da madre convalescente della stessa malattia. Lattante 33:767–771
Weber DJ, Rutala WA, Orenstein WA (1991) Prevention of mumps, measles, and rubella among hospital personnel. J Pediatr 119:322–326
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Lacour, M., Maherzi, M., Vienny, H. et al. Thrombocytopenia in a case of neonatal mumps infection: Evidence for further clinical presentations. Eur J Pediatr 152, 739–741 (1993). https://doi.org/10.1007/BF01953989
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DOI: https://doi.org/10.1007/BF01953989