Summary
A crude extract of the venom of the marine snailConus textile Linné caused a powerful contraction in the guinea-pig isolated ileum. The extract of the venom has been fractionated, and the fractions monitored by the contractile effect. Arachidonic acid was shown to be present as an active substance.
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Acknowledgment. We are grateful to Mr Z. Nagahama of Okinawa island for suppling specimens ofC. textile and to Dr T. Higashijima and Prof. T. Miyazawa (Department of Biophysics and Biochemistry, Tokyo University) for 270 MHz1H-NMR-measurements.
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Nakamura, H., Kobayashi, J., Ohizumi, Y. et al. The occurrence of arachidonic acid in the venom duct of the marine snailConus textile. Experientia 38, 897 (1982). https://doi.org/10.1007/BF01953639
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DOI: https://doi.org/10.1007/BF01953639