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Two novel prolactin release-inhibiting 8α-amino-ergolines

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Summary

Prolactin secretion inhibition and changes in striatal dopamine metabolism in rats were compared after the administration of 8a-amino-ergoline CH 29-717 and 2 derivates. CQ 32-084 was similar to but less potent than CH 29-717. while 32-085, the 1-methyl derivative, showed delayed dopaminomimetic effects.

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Authors and Affiliations

  1. Preclinical Research, Pharmaceutical Division, Sandoz Ltd, CH-4002, Basel, Switzerland

    E. Flückiger, U. Briner, H. R. Bürki, P. Marbach, H. R. Wagner & W. Doepfner

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  1. E. Flückiger
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  2. U. Briner
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  3. H. R. Bürki
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  4. P. Marbach
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  5. H. R. Wagner
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  6. W. Doepfner
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Flückiger, E., Briner, U., Bürki, H.R. et al. Two novel prolactin release-inhibiting 8α-amino-ergolines. Experientia 35, 1677–1678 (1979). https://doi.org/10.1007/BF01953267

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  • DOI: https://doi.org/10.1007/BF01953267

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