Abstract
To study the origins of biologically active substances in marine sponges, a carotenoid produced by a marine bacterium,Pseudomonas sp. strain number KK10206C, which was associated with a marine sponge,Halichondra okadai, was investigated. A visible absorption spectrum-guided isolation procedure led to the isolation of a novel C50-carotenoid, okadaxanthin. Its structure, 2,2′-bis(4-hydroxy-2-methyl-2-butenyl)-ε,ε-carotene, was elucidated mainly by spectroscopic methods. Okadaxanthin turned out to be a potent singlet oxygen quencher, approximately 10 times as strong as α-tocopherol.
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Miki, W., Otaki, N., Yokoyama, A. et al. Okadaxanthin, a novel C50-carotenoid from a bacterium,Pseudomonas sp. KK10206C associated with marine sponge,Halichondria okadai . Experientia 50, 684–686 (1994). https://doi.org/10.1007/BF01952874
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DOI: https://doi.org/10.1007/BF01952874