Summary
In the subretinal space of albino mice, macrophages appear from the time of eye opening and increase in number for 6 months; thereafter they decline with age. Dark rearing retards the accumulation of these cells, and exposure to constant light results in a rapid increase. Observations suggest that macrophages appear as a response to visual cell decay in albino mice and supplement the phagocytic activity of the pigment epithelium.
Literatur
Sanyal, S., Histochemie29 (1972) 28.
Hume, D.A., Perry, V.H., and Gordon, S., J. Cell Biol.97 (1983) 253.
Sanyal, S., De Ruiter, A., and Hawkins, R.K., J. comp. Neurol.194 (1980) 193.
LaVail, M.M., Blanks, J.C., and Mullen, R.J., J. comp. Neurol.212 (1982) 217.
Ling, E.A., Archvm histol. jap.44 (1981) 167.
Ling, E.A., Archvm histol. jap.45 (1982) 37.
Essner, E. and Gorrin, G., Invest. Ophthal. vis. Sci.18 (1979) 11.
O'Steen, W.K., and Karcioglu, Z.A., Am. J. Anat.139 (1974) 503.
Gloor, B.P., Albrecht v. Graefes Arch. Ophthal.190 (1974) 183.
Braekevelt, C.R., Vision Res.20 (1980) 495.
Sanyal, S., and Jansen, H.G., Neurosci. Lett.21 (1981) 23.
Graham, R.C., and Karnovsky, M.J., J. Histochem. Cytochem.14 (1966) 291.
Ogawa, T., Koerten, H.G., and Daems, W.Th., Cell Tiss. Res.188 (1978) 361.
Hayashi, M., J. Histochem. Cytochem.13 (1965) 355.
Barka, T., and Anderson, P.J., J. Histochem. Cytochem.10 (1962). 741.
Bhattacharjee, J. and Sanyal, S., Histochemistry46 (1975) 53.
Novikoff, A.B., and Goldfischer, S., Proc. natl Acad. Sci. USA47 (1961) 802.
Sanyal, S., and De Ruiter, A., in preparation.
Daems, W.Th., and Koerten, H.K., Cell Tiss. Res.190 (1978) 47.
Young, R.W., J. Cell Biol.33 (1967) 61.
Author information
Authors and Affiliations
Additional information
We thank R.K. Hawkins for efficient management of the animal colony, H.G. Jansen for cooperation in the use of electron microscope and Ms Paula van Alphen for help in preparation of the illustrations.
Rights and permissions
About this article
Cite this article
Sanyal, S., De Ruiter, A. & Dees, C. Light dependent accumulation of macrophages at the photoreceptor-pigment epithelial interface in the retina of albino mice. Experientia 40, 852–854 (1984). https://doi.org/10.1007/BF01951991
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01951991