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Nucleosides and nucleotides. Part 5. The stereochemistry of oligonucleotides consisting of 2′-deoxy-α-d-ribosides, a study withDreiding stereomodels

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Zusammenfassung

Studien anhand vonDreiding Stereomodellen zeigen, dass die Bildung von helixartigen Sekundärstrukturen durch Basenpaarung und Basenstapelung nicht auf Polynucleotide mit β-ständig angeordneten Basen (Konfiguration wie sie in den Nukleinsäuren gefunden wird) beschränkt ist. Auch Polymere aus lauter α-Nucleotideinheiten scheinen dazu befähigt zu sein.

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  22. Acknowledgments. The autheor thanks Prof.Ch. Tamm for his continuous interest and for encouraging discussions. The investigation was supported by the ‘Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung’ (project Nr. 2.460.71).

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  1. Institut für Organische Chemie der Universität, St. Johannsring 19, CH-4056, Basel, (Switzerland)

    U. Séquin

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  1. U. Séquin
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Part 4:R. Glaser, U. Séquin andCh. Tamm, Helv. chim. Acta56, 654 (1973).

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Séquin, U. Nucleosides and nucleotides. Part 5. The stereochemistry of oligonucleotides consisting of 2′-deoxy-α-d-ribosides, a study withDreiding stereomodels. Experientia 29, 1059–1062 (1973). https://doi.org/10.1007/BF01946717

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