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Suppression of delayed type hypersensitivity of mice by lead

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Summary

Application of lead suppressed the delayed type hypersensitivity (DTH) of mice induced by sheep red blood cells (SRBC). Inhibition of elicitation of DTH in primary as well as in secondary response was correlated with the concentration of lead in the blood of the mice.

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Acknowledgments. Supported by the ‘Georg-und-Agnes-Blumenthal-Stiftung’ and the ‘Verein für Wasser-, Boden- und Lufthygiene’. We thank Miss Schachtschneider for the excellent technical assistance.

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Müller, S., Gillert, K.E., Krause, C. et al. Suppression of delayed type hypersensitivity of mice by lead. Experientia 33, 667–668 (1977). https://doi.org/10.1007/BF01946564

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