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In vivo generation of hydrogen peroxide from 6-hydroxydopamine

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Zusammenfassung

Es gelang, die Erythrocytenkatalase der Maus durch Injektion von 6-Hydroxydopamin und in Gegenwart von 3-Amino-1,2,4-triazol zu hemmen, was auf die Wasserstoffperoxyd-Entwicklung hinweist und mit der Rolle des H2O2 bei der Degeneration der Nervenenden durch 6-Hydroxydopamin in Einklang steht.

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Authors and Affiliations

  1. Departments of Neurology, Psychiatry and Biochemistry, College of Physicians and Surgeons, Columbia University, 10032, New York, New York, USA

    R. E. Heikkila & G. Cohen

Authors
  1. R. E. Heikkila
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  2. G. Cohen
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Heikkila, R.E., Cohen, G. In vivo generation of hydrogen peroxide from 6-hydroxydopamine. Experientia 28, 1197–1198 (1972). https://doi.org/10.1007/BF01946168

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  • DOI: https://doi.org/10.1007/BF01946168

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