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Sister chromatid exchanges in human lymphocytes exposed to 8-methoxypsoralen and long wave UV radiation prior to incorporation of bromodeoxyuridine

  • Specialia
  • Anatomica, Histologica, Embryologica, Carcinologica
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Summary

Human lymphocytes exposed to the effects of long wave UV radiation in the presence of 8-methoxypsoralen prior to stimulation by PHA show dose related sister chromatid exchanges after 2 replication cycles in vitro. This has implications for interpreting the repair processes involved and for monitoring DNA damaging agents in vivo.

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Authors and Affiliations

  1. Cytogenetics Laboratory, Department of Pathology and Department of Dermatology, Ninewells Medical School, University of Dundee, DD2 1UB, Dundee, Scotland

    D. Mourelatos, M. J. W. Faed & B. E. Johnson

Authors
  1. D. Mourelatos
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  2. M. J. W. Faed
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  3. B. E. Johnson
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Mourelatos, D., Faed, M.J.W. & Johnson, B.E. Sister chromatid exchanges in human lymphocytes exposed to 8-methoxypsoralen and long wave UV radiation prior to incorporation of bromodeoxyuridine. Experientia 33, 1091–1093 (1977). https://doi.org/10.1007/BF01945989

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  • DOI: https://doi.org/10.1007/BF01945989

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