Summary
During a 4-week period, the electroshock seizure threshold (EST) of R Amsterdam rats was determined. When alloxan induced diabetes, the EST values significantly decreased, while in the alloxan-treated non-diabetic group they remained unchanged. The results suggest that diabetes induces increased excitability in the central nervous system.
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Koltai, M., Minker, E. Changes of electro-shock seizure threshold in alloxan diabetic rats. Experientia 31, 1369 (1975). https://doi.org/10.1007/BF01945833
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DOI: https://doi.org/10.1007/BF01945833