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Über die Ätiologie der Lippen-Kieferspaltformen und Gaumenspalten beim Menschen und im Tierexperiment

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Summary

Only formhydroxamic acid and its certain derivatives induce in rats cleft-lip and palate (CLP) after treatment during early embryonic developmental phase. Other hydroxamic acids and formamide-derivatives caused different malformations but no CLP. Also unknown in rats in the hereditary CLP. The possible causes of CLP in rats are compared with these in mice and men.

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Authors and Affiliations

  1. Nordwestdeutsche Kieferklinik, Chirurgische Abteilung der Universitätsklinik und Poliklinik für Zahn-, Mund-und Kieferkrankheiten, Martinistrasse 52, D-2000, Hamburg 20, Deutschland

    G. Pfeifer & Th. von Kreybig

Authors
  1. G. Pfeifer
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  2. Th. von Kreybig
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Pfeifer, G., von Kreybig, T. Über die Ätiologie der Lippen-Kieferspaltformen und Gaumenspalten beim Menschen und im Tierexperiment. Experientia 29, 225–228 (1973). https://doi.org/10.1007/BF01945491

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  • DOI: https://doi.org/10.1007/BF01945491

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