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Effect of scorpion venom fromTityus serrulatus (Tityustoxin) on the acetylcholine release and fine structure of the nerve terminals

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Zusammenfassung

Nachweis, dass ein Giftstoff des südamerikanischen SkorpionsTityus serrulatus auch in vitro am isolierten Meerschweinchendarm zu stark erhöhtem Acetylcholinausstoss führt der bei Kalziumentzug und Blockade des Natriumeinstroms durch Tetrodotoxin blockiert werden kann. Elektronenoptisch sind im Mäusezwerchfellpräparat nur im präsynaptischen Gebiet pathologische Veränderungen zu sehen.

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Authors and Affiliations

  1. Departments of Biochemistry and Morphology, Faculty of Medicine, University of São Paulo, Caixa postal 301, 14.100, Ribeirão Preto, S. P., Brazil

    C. R. Diniz, Aurea F. Pimenta, J. Coutinho Netto, S. Pompolo, M. V. Gomez & G. M. Böhm

Authors
  1. C. R. Diniz
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  2. Aurea F. Pimenta
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  3. J. Coutinho Netto
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  4. S. Pompolo
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  5. M. V. Gomez
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  6. G. M. Böhm
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Additional information

This work was supported by a grant (Biol. No. 72/134) of the State of São Paulo Research Foundation.

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Diniz, C.R., Pimenta, A.F., Netto, J.C. et al. Effect of scorpion venom fromTityus serrulatus (Tityustoxin) on the acetylcholine release and fine structure of the nerve terminals. Experientia 30, 1304–1305 (1974). https://doi.org/10.1007/BF01945198

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  • DOI: https://doi.org/10.1007/BF01945198

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