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Leukocytes and prostaglandins in acute inflammation

  • Biologica
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Zusammenfassung

Bei einer akuten Entzündung wurde der zeitliche Verlauf der Prostaglandinfreisetzung, Granulozyteneinwanderung und Gefässpermeabilität verfolgt. Die höchsten Prostaglandinkonzentrationen wurden vor der Einwanderung von Granulozyten und vor einer massiven Steigerung der Gefässpermeabilität beobachtet. Dieser Befund spricht gegen die Behauptung, dass Granulozyten wesentlich an der Freisetzung von Prostaglandin beteiligt sind.

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Author notes

  1. K. Brune

    Present address: Department of Pharmacology of the University, Katharinenstrasse 29, D-78, Freiburg, Federal Republic of Germany

Authors and Affiliations

  1. Department of Pharmacology of the University Biocenter, Klingelbergstrasse 70, CH-4056, Basel, Switzerland

    M. Glatt, B. Peskar & K. Brune

  2. Department of Pharmacology of the University, Katharinenstrasse 29, D-78, Freiburg, Federal Republic of Germany

    M. Glatt & B. Peskar

Authors
  1. M. Glatt
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  2. B. Peskar
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  3. K. Brune
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Additional information

Acknowledgment: We thank Dr.J. Pike, the Upjohn Co., for providing prostaglandins.

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Glatt, M., Peskar, B. & Brune, K. Leukocytes and prostaglandins in acute inflammation. Experientia 30, 1257–1259 (1974). https://doi.org/10.1007/BF01945171

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  • DOI: https://doi.org/10.1007/BF01945171

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