Summary
Effect of preoperative stress on serum cholesterol level in 65 patients of different age groups in a surgical ward, has been studied. In all age groups, statistically significant rise of cholesterol in serum preoperatively was noticed as compared with serum cholesterol level at the time of discharge from hospital. The preoperative rise of cholesterol varied from 39 to 56.9% in this series. These findings support previous reports of the effect of mental tension on serum cholesterol level.
Similar content being viewed by others
References
M. R. Friedman, R. H. Rosenman and V. Coroll, Circulation17, 852 (1958).
C. B. Thomas and E. A. Murphy, J. chron. Dis.8, 661 (1958).
P. T. Wertlake, A. A. Wilcox, M. I. Haley and J. E. Peterson, Proc. Soc. exptl Biol. Med.97, 163 (1958).
S. M. Grundy and A. C. Griffin, Circulation19, 496 (1959).
S. M. Grundy and A. C. Griffin, J. Am. med. Ass.171, 1794 (1959).
W. J. Kuhl, Jr, E. M. Beck, H. Gershberg, E. Street and E. P. Ralli, Metabolism4, 143 (1955).
F. Dreyfuss and J. W. Czaczkes, A. M. A. Archs intern. Med.103, 708 (1959).
H. Selye, in: Stress Acts, p. 278. INC Medical publishers, 1950.
D. E. Beischer, J. Aviat. Med.27, 260 (1955).
G. V. Mann and H. S. White, Metabolism2, 47 (1957).
L. A. Carlson, L. Levi and L. Oro, J. clin. Invest.47, 1795 (1968).
L. H. Kyle, W. C. Hess and W. P. Walsh, J. Lab. clin. Med.39, 605 (1952).
B. Zak, Am. J. clin. Path.27, 583 (1957).
T. G. Minlin and K. Chen, Drug Res.1, 128 (1959).
S. H. Rubin, J. biol. Chem.131, 619 (1949).
H. Buhl, Münch. Med. Wschr.108, 2490 (1960).
H. A. Harper and P. Mayes, in: Review of Physiological Chemistry, 14th ed., p. 268 (1973).
Author information
Authors and Affiliations
Additional information
Authors acknowledge with pleasure the useful discussions with Dr A. K. Ganguly, Prof. of Physiology, Government Medical College, Surat, Dr T. H. Rindani, Medical Director, Jaslok Hospital, Bombay. Statistical analysis by Shri P. Gopinath and technical assistance of Shri N. T. Pabani.
Rights and permissions
About this article
Cite this article
Sane, A.S., Kukreti, S.C. Effect of preoperative stress on serum cholesterol level in humans. Experientia 34, 213–214 (1978). https://doi.org/10.1007/BF01944684
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01944684