Skip to main content
SpringerLink
Log in

Effect of nerve stimulation, denervation, and duct ligation, on kallikrein content and duct cell granules of the cat's submandibular gland

  • Published:
Experientia Aims and scope Submit manuscript

Summary

Various procedures which reduce or deplete the kallikrein content of the cat's submandibular gland correspondingly reduce the number of apical granules in the striated duct cells. The kallikrein content is greatly reduced after chronic parasympathetic but not after sympathetic nerve section which suggests that the parasympathetic innervation is required for synthesis or storage of this enzyme.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. E. K. Frey, H. Kraut, E. Werle, R. Vogel, G. Zickgraf-Rüdel and I. Trautschold, in: Das Kallikrein-Kinin-System und seine Inhibitoren. Enke, Stuttgart 1968.

    Google Scholar 

  2. M. Schachter, Physiol. Rev.49, 409 (1969).

    Article  Google Scholar 

  3. K. D. Bhoola and C. W. Ogle, J. Physiol., Lond.184, 663 (1966).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. E. G. Erdös, L. L. Tague and I. Miwa, Biochem. Pharmac.17, 667 (1968).

    Article  Google Scholar 

  5. S. Barton, E. J. Sanders, M. Schachter and M. Uddin, J. Physiol., Lond.251, 363 (1975).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. J. R. Garrett and A. Kidd, Cell Tiss. Res.161, 71 (1975).

    Article  CAS  Google Scholar 

  7. M. Schachter, in: Handbook of Experimental Pharmacology, p. 400. Springer-Verlag, Heidelberg 1970.

    Google Scholar 

  8. S. M. Hilton, in: Handbook of Experimental Pharmacology, p. 389. Springer-Verlag, Heidelberg 1970.

    Google Scholar 

  9. K. D. Bhoola, Biochem. Pharmac.18, 1252 (1969).

    Article  CAS  Google Scholar 

  10. P. Brandtzaeg, K. M. Gautvik, K. Nustad and J. V. Pierce, Br. J. Pharmac.56, 155 (1976).

    Article  CAS  Google Scholar 

  11. S. Beilenson, M. Schachter and L. H. Smaje, J. Physiol., Lond.199, 303 (1968).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. M. Schachter, S. Barton and E. Karpinski, Experientia29, 1498 (1973).

    Article  CAS  PubMed  Google Scholar 

  13. K. D. Bhoola and P. F. Heap, J. Physiol., Lond.210, 421 (1970).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. M. S. Pollack and J. W. C. Bird, Am. J. Physiol.215, 716 (1968).

    Article  CAS  PubMed  Google Scholar 

  15. N. Emmelin and U. Trendelenburg, Ergebn. Physiol.66, 147 (1972).

    CAS  PubMed  Google Scholar 

  16. S. Barton, E. Karpinski, C. Moriwaki and M. Schachter, J. Physiol., Lond.261, 523 (1976).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, University of Alberta, T6G 2H7, Edmonton, Alberta, Canada

    M. Schachter, Susanne Barton, M. Uddin, E. Karpinski & E. J. Sanders

Authors
  1. M. Schachter
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Susanne Barton
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Uddin
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. E. Karpinski
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. E. J. Sanders
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

We wish to acknowledge the valuable assistance of Dr T. Nihei and Mr. J. Wimal in some of the enzyme measurements.

This work was supported by grants from the Medical Research Council of Canada and the Alberta Heart Foundation.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schachter, M., Barton, S., Uddin, M. et al. Effect of nerve stimulation, denervation, and duct ligation, on kallikrein content and duct cell granules of the cat's submandibular gland. Experientia 33, 746–748 (1977). https://doi.org/10.1007/BF01944167

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01944167

Keywords

Search

Navigation