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Ornithine decarboxylase, S-adenosyl-L-methionine decarboxylase and arginine decarboxylase fromMycobacterium bovis (BCG)

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Summary

Ornithine decarboxylase (ODC), S-adenosyl-L-methionine decarboxylase (AMDC) and arginine decarboxylase (ADC) activities were detected for the first time in extracts ofMycobacterium bovis (BCG). All the decarboxylases differed from corresponding known bacterial decarboxylases in that: a) ODC did not require GTP for activity; b) ODC was not inhibited by any known inhibitor of bacterial ODCs; c) AMDC and ADC did not require Mg2+-ion for activity and were not markedly inhibited by any known inhibitor of the decarboxylases of other bacteria.

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Authors and Affiliations

  1. Department of Pharmacology and Toxicology, College of Veterinary Medicine, SF-00550, Helsinki, Finland

    L. Paulin, E. Brander & H. Pösö

  2. National Public Health Institute, SF-00280, Helsinki, Finland

    L. Paulin, E. Brander & H. Pösö

Authors
  1. L. Paulin
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  2. E. Brander
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  3. H. Pösö
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Paulin, L., Brander, E. & Pösö, H. Ornithine decarboxylase, S-adenosyl-L-methionine decarboxylase and arginine decarboxylase fromMycobacterium bovis (BCG). Experientia 43, 174–176 (1987). https://doi.org/10.1007/BF01942840

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  • DOI: https://doi.org/10.1007/BF01942840

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