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Deficiency of membrane-bound dipeptidyl aminopeptidase IV in a certain rat strain

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The activity of membrane-bound dipeptidyl aminopeptidase IV (EC 3.4.14.5) was found to be markedly reduced in the Fischer 344 rat strain compared with that in the Wistar strain. Analysis of membrane proteins by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Ouchterlony immunodiffusion revealed the specific absence of this enzyme molecule in the Fischer 344 strain.

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Authors and Affiliations

  1. Department of Clinical Biochemistry, Hokkaido Institute of Pharmaceutical Sciences, 7-1 Katsuraoka-cho, 047-02, Otaru, Japan

    Y. Watanabe, T. Kojima & Y. Fujimoto

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  1. Y. Watanabe
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  2. T. Kojima
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  3. Y. Fujimoto
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Watanabe, Y., Kojima, T. & Fujimoto, Y. Deficiency of membrane-bound dipeptidyl aminopeptidase IV in a certain rat strain. Experientia 43, 400–401 (1987). https://doi.org/10.1007/BF01940426

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